Cure My Disease

Don't miss your cure!

 Log in / Sign up

Which ultrasound tool spots fluid overload sooner in septic shock?

NCT ID NCT07797751

Diagnosis Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial tests two ultrasound techniques to see which one detects fluid overload earlier in adults with septic shock who need fluid resuscitation. One method uses lung ultrasound, the other measures blood flow velocity in the heart's main outflow tract. Researchers will compare how reliably each approach spots early signs that the body is retaining too much fluid. The goal is to find a faster, more accurate way to guide fluid treatment in critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lung ultrasonography and left ventricular outflow tract velocity time integral (LVOT-VTI) measurement
What this could lead to
If one method proves more reliable, doctors could spot fluid overload earlier in septic shock patients, potentially reducing complications and improving care.
What could go wrong
This is a small, early study with 30 participants, so results may not apply broadly. The methods require skill, and patient factors like obesity or heart disease could limit accuracy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patient with septic shock applied by inclusion \& exclusion criteria .

Ages

18 hours and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients aged ≥ 18 years with septic shock. 2. Mean arterial pressure (MAP) \<65 mmHg. 3. Need fluid resuscitation. Exclusion Criteria: 1. Patient \<18 years. 2. Refusal of patient or relative to participate in the study. 3. Other types of shock. 4. Morbid obesity. 5. Valvular heart disease including severe aortic and mitral stenosis) and (severe aortic and mitral regurgitation). 7.Patients with heart failure with preserved or reduced Ejection fraction. 8.Burn patients. 9.End stage renal disease with regular hemodialysis patient. 11.Patients with massive pleural effusion. 12. patients with septic cardiomyopathy. 13.patients with massive ascites. 14. patient on high positive end expiratory pressure or with acute respiratory distress syndrome (ARDS). 15. Patients with right ventricular failure \& pulmonary hypertension. 16. Patients with pneumonia and interstitial lung diseases. 17. Ventilated patients. 18. Poor echo window patients.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Fluid reponsiveness are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fluid reponsiveness Septic shock

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.