Could a simple pill combo slash heart attacks and strokes?

NCT ID NCT06930885

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tests whether a daily polypill (combining several heart medications) plus colchicine can reduce major heart problems like heart attacks, strokes, and amputations in people with established heart or artery disease. About 7,700 to 10,800 adults aged 45 and older with a history of heart events or procedures will take part. The goal is to see if this combination offers better protection than current standard care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CIPES - Centro Internacional de Pesquisa Clínica

    RECRUITING

    São José dos Campos, São Paulo, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CMEP - Centro Multidisciplinar de Ensino especializado e Pesquisa

    RECRUITING

    Joinville, Santa Catarina, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro de Pesquisa Cardiolima

    RECRUITING

    Teresina, Piauí, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro de Pesquisa Cetrus

    RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro de Pesquisas Clínicas Dr. Marco Mota

    RECRUITING

    Maceió, Alabama, 57051160, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Empresa Brasileira de Serviços Hospitalares - EBSERCH - Hospital de Ensino Dr. Washington Antônio de Barros- HU-UNIVASF

    RECRUITING

    Petrolina, Pernambuco, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundação Faculdade Regional de Medicina São José do Rio Preto

    RECRUITING

    São José do Rio Preto, São Paulo, 15.090-000, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundação Técnico Educacional Souza Marques

    RECRUITING

    Rio de Janeiro, Rio de Janeiro, 22.793-140, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fundação Universitária de Cardiologia - ICFUC

    RECRUITING

    Porto Alegre, Rio Grande do Sul, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hcor

    RECRUITING

    São Paulo, São Paulo, 04004-030, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitário São Francisco na Providência de Deus

    RECRUITING

    Bragança Paulista, São Paulo, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto de Pesquisa e Ensino em Saúde - IPES

    RECRUITING

    Porto Velho, Rondônia, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Secretária da Saúde do Estado do Ceará - Hospital de Messejana Dr. Carlos Alberto Studart Gomes

    RECRUITING

    Messejana, Ceará, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.