ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Clinical trials for ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD) explained in plain language.
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New pill aims to cut heart attacks in people with 'Hidden' cholesterol risk
Disease control Recruiting nowThis Phase 3 trial tests an oral drug called muvalaplin in over 10,000 adults with high levels of lipoprotein(a), a genetic risk factor for heart disease and stroke. Participants either have had a prior cardiovascular event or are at high risk for a first one. The study measures …
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug duo aims to slash heart disease risk by targeting hidden cholesterol
Disease control Recruiting nowThis study tests whether adding pelacarsen to inclisiran can further lower a type of cholesterol called Lp(a) in people with heart disease. About 340 adults with high Lp(a) and LDL-C will receive either pelacarsen or a placebo, plus inclisiran. The main goal is to see if Lp(a) le…
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for heart patients: pelacarsen available through special program
Disease control AVAILABLEThis program provides access to pelacarsen, a drug for atherosclerotic cardiovascular disease, for patients who have no other treatment options and cannot join a clinical trial. It is for those with serious or life-threatening conditions where the potential benefit outweighs the …
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Double-Drug attack on cholesterol: could two be better than one?
Disease control Recruiting nowThis study looks at whether combining two different cholesterol-lowering drugs (inclisiran and alirocumab) works better than using either alone. About 60 adults with high heart risk who cannot take statins will be assigned to one of three groups. The goal is to see if the combo l…
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Phase: PHASE4 • Sponsor: University Medical Centre Ljubljana • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a single daily pill slash heart disease risks?
Disease control Recruiting nowThe EPOCA trial is testing whether a daily 'polypill' (combining blood pressure, cholesterol, and blood-thinning medications) plus the anti-inflammatory drug colchicine can reduce major heart and limb events in people with established heart disease. Over 7,700 participants aged 4…
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Phase: PHASE3 • Sponsor: Hospital do Coracao • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could a Half-Dose of aspirin protect elderly hearts just as well?
Knowledge-focused Recruiting nowThis study looks at whether a lower daily dose of aspirin (50 mg) is as effective and safer than the standard dose (100 mg) for preventing heart attacks and strokes in Chinese patients aged 60 and older with heart disease. Researchers will follow over 5,400 participants for up to…
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Sponsor: Peking University First Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Hidden heart risks in inherited high cholesterol: new study aims to find them early
Knowledge-focused Recruiting nowThis study is for people with familial hypercholesterolemia (inherited high cholesterol) who have no heart symptoms yet. Researchers will use a special CT scan to check for hidden blockages in the heart arteries. The goal is to learn which factors are linked to these blockages, s…
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Simple blood test may spot hidden heart risk in arthritis patients
Knowledge-focused Recruiting nowPeople with rheumatoid arthritis have double the risk of heart attack. This study is testing whether a blood test for troponin, along with a heart scan, can catch heart disease early. Researchers will enroll 120 adults aged 40-79 with RA and at least one heart risk factor. The go…
Matched conditions: ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD)
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC