Blood test may predict aneurysm surgery need in marfan patients
NCT ID NCT05700175
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study looks for biological markers in the blood and tissue of adults with Marfan syndrome that could signal when an aortic aneurysm is dangerous enough to require surgery. Researchers will compare three groups of Marfan patients: those without aortic aneurysms, those with stable aneurysms, and those needing surgery. By analyzing gene activity and other molecules, they hope to find a signature that improves current monitoring and treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a blood test that helps doctors predict which Marfan patients need aortic surgery earlier.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear biomarkers, and any future test would require years of additional validation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Pregnancy-Related Aortic Dissection Registry NCT07672210
- Ketogenic Diet for Marfan Aortic Dissection (NCT07495267)
- Marfan Syndrome Biological Collection Study | NCT04970459
- Marfan&Moves: Exercise Program for Kids with Mar NCT05838235
- Physical Activity in Marfan Syndrome Study | NCT07419386
- Marfan Syndrome Rehab Study for Kids & Young Adu NCT03236571
Contacts and locations
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Locations
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Irccs Policlinico San Donato
San Donato Milanese, Milan, 20097, Italy