New drug could extend window for treating deadly stroke
NCT ID NCT05105633
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial is testing a drug called tenecteplase for people with a severe stroke caused by a blockage in the basilar artery at the back of the brain. About 688 participants will receive either tenecteplase or standard care within 24 hours of symptoms starting, followed by a clot-removal procedure if needed. The goal is to see if tenecteplase helps more people recover with little or no disability at 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tenecteplase (a clot-busting drug given as a quick injection)
What this could lead to
If it works, this could offer a more effective clot-busting treatment for a severe type of stroke, potentially helping more people recover without disability.
What could go wrong
This is an early-to-mid stage trial, so results are not guaranteed. The drug may not improve outcomes and could increase the risk of bleeding in the brain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Locations
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Alfred Health
RECRUITINGMelbourne, Victoria, Australia
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Austin Hospital
RECRUITINGMelbourne, Victoria, Australia
Contact Email: •••••@•••••
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Bankstown-Lidcombe Hospital
NOT_YET_RECRUITINGBankstown, New South Wales, Australia
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Box Hill Hospital
RECRUITINGMelbourne, Victoria, Australia
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Fiona Stanley Hospital
RECRUITINGMurdoch, Western Australia, 6150, Australia
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Gold Coast Hospital
NOT_YET_RECRUITINGGold Coast, Queensland, Australia
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Grampians Health
RECRUITINGBallarat, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Geral de Fortaleza
RECRUITINGFortaleza, Brazil
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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John Hunter Hospital
NOT_YET_RECRUITINGNewcastle, New South Wales, Australia
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Liverpool Hospital
RECRUITINGSydney, New South Wales, Australia
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Contact Email: •••••@•••••
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Monash Health
NOT_YET_RECRUITINGMelbourne, Victoria, Australia
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Northern Hospital
RECRUITINGMelbourne, Australia
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Princess Alexandra Hospital
RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Royal Adelaide Hospital
RECRUITINGAdelaide, South Australia, Australia
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Royal Melbourne Hospital
RECRUITINGMelbourne, Victoria, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tours University Hospital
RECRUITINGTours, France
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Western Health
RECRUITINGMelbourne, Victoria, Australia
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Contact