New scan could spot hidden stroke risk in blocked arteries

NCT ID NCT05838547

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a new type of PET-MR scan can help predict stroke risk in people with significant narrowing of the carotid artery (the main artery in the neck) who have not yet had symptoms. Researchers will give participants an injection of a radioactive tracer and take images of their arteries. They will then follow participants for up to 18 months to see who has a stroke or needs treatment, to see if the scan signal correlates with risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

64Cu-25%-CANF-Comb (a radioactive tracer for PET imaging)

What this could lead to

If successful, this could lead to a better way to identify which patients with carotid artery narrowing are at highest risk for stroke, helping guide treatment decisions.

What could go wrong

This is an early observational study, not a treatment trial. The imaging technique may not prove accurate enough to predict risk, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder carotid artery disorder carotid stenosis stroke disorder vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Email: •••••@•••••

  • Washington University in St. Louis

    RECRUITING

    St Louis, Missouri, 63130-2344, United States

    Contact Email: •••••@•••••