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Could a green tea compound prevent second heart attacks?

NCT ID NCT06590012

Ongoing Disease control Sponsor: Institute for Atherosclerosis Research, Russia Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This trial tests whether a dietary supplement called Tertinat, containing epigallocatechin-3-gallate, can reduce major heart problems in people with atherosclerosis who have recently had bypass or stent surgery. Over two years, participants take either the supplement or a placebo alongside standard care. The study measures heart attacks, strokes, unstable angina, heart failure, and the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a dietary supplement called Tertinat, which contains epigallocatechin-3-gallate
What this could lead to
If it works, this could point toward a simple dietary supplement that lowers the risk of heart attacks, strokes, and repeat surgeries in people with hardened arteries.
What could go wrong
This is a Phase 2 trial, so it is still early. The supplement may not reduce heart events as hoped, and results may not apply to everyone with atherosclerosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atherosclerosis carotid artery disorder carotid stenosis coronary artery disorder coronary atherosclerosis peripheral arterial disease renal artery atheroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATHEROSCLEROSES, CORONARY ATHEROSCLEROSIS CAROTID ATHEROSCLEROSIS

Contacts and locations

Locations

  • A. V. Vishnevsky National Medical Research Center of Surgery (Federal State Budgetary Institution)

    Moscow, 117997, Russia

  • Cardiology Research Institute - Branch of the Federal State Budgetary Scientific Institution "Tomsk National Research Medical Center of the Russian Academy of Sciences"

    Tomsk, 634012, Russia

  • City Polyclinic No. 109 (State Budgetary Healthcare Institution)

    Saint Petersburg, 192283, Russia

  • LLC "RC Medical"

    Novosibirsk, 630005, Russia

  • Lipetsk Regional Clinical Hospital

    Lipetsk, 398055, Russia

  • Llc "Sfera-Med"

    Saint Petersburg, 197342, Russia

  • M. F. Vladimirsky Moscow Regional Research Clinical Institute

    Moscow, 129110, Russia

  • N. N. Burdenko Voronezh State Medical University

    Voronezh, 394036, Russia

  • Research Institute for Complex Issues of Cardiovascular Diseases

    Kemerovo, 650000, Russia

  • State Autonomous Healthcare Institution "Interregional Clinical Diagnostic Center"

    Kazan', 420101, Russia

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