Gene therapy builds CAR-T cells inside the body to fight myeloma

NCT ID NCT07075185

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 31 times

Summary

This early-stage study tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or not responded to treatment. Instead of removing cells and engineering them in a lab, this therapy delivers a gene directly into the body to create cancer-fighting CAR-T cells. The main goal is to check safety and find the right dose in about 70 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Providence Portland Medical Center

    RECRUITING

    Portland, Oregon, 97213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Alfred Paula Fox Melanoma and Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Royal Prince Alfred

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.