Gene therapy builds Cancer-Killing cells inside you – no lab needed

NCT ID NCT07075185

Recruiting now Disease control Sponsor: Kelonia Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This early-stage trial tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or stopped responding to treatment. Instead of removing cells and engineering them in a lab, this therapy works inside the body to create special immune cells that target and attack the cancer. The study will enroll about 70 participants to check safety and find the right dose.

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Conditions

The condition(s) this trial relates to.

Blood Protein Disorders disease hematologic disorder immune system disorder immunoproliferative disorder lymphoproliferative syndrome monoclonal gammopathy monoclonal paraproteinemia disease neoplasm Neoplasms by Histologic Type plasma cell myeloma refractory plasma cell neoplasm vascular disorder vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD PROTEIN DISORDERS GENE THERAPY HEMATOLOGIC DISEASE AND DISORDERS HEMOSTATIC DISORDERS IMMUNE SYSTEM DISEASE IMMUNOPROLIFERATIVE DISORDERS LYMPHOPROLIFERATIVE DISORDERS MULTIPLE MYELOMA IN RELAPSE MULTIPLE MYELOMA PROGRESSION MYELOMA MULTIPLE NEOPLASM NEOPLASMS BY HISTOLOGIC TYPE PARAPROTEINEMIAS VASCULAR DISORDER

Contacts and locations

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Locations

City of Hope
RECRUITING

Duarte, California, 91010, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States

Contact Email: •••••@•••••
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, Victoria, 3000, Australia
Providence Portland Medical Center
RECRUITING

Portland, Oregon, 97213, United States

Contact Email: •••••@•••••
Stanford University
RECRUITING

Palo Alto, California, 94304, United States
The Alfred Paula Fox Melanoma and Cancer Centre
RECRUITING

Melbourne, Victoria, 3004, Australia
The Royal Prince Alfred
RECRUITING

Camperdown, New South Wales, 2050, Australia
UCSF
RECRUITING

San Francisco, California, 94143, United States

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