MYELOMA MULTIPLE

This early-stage study tests a new gene therapy called KLN-1010 for people with multiple myeloma that has returned or not responded to treatment. Instead of removing cells, modifying them in a lab, and putting them back, this therapy aims to create cancer-fighting CAR-T cells dir…

This study tests whether adding belantamab mafodotin to standard lenalidomide therapy after a stem cell transplant can turn residual cancer cells undetectable in people with newly diagnosed multiple myeloma. About 94 adults who have already had a transplant and still have some si…

This early-stage study tests an experimental pill called KTX-1001 in people with multiple myeloma that has returned or not responded to at least three prior treatments. The main goals are to check safety and find the right dose, with early signs of tumor shrinkage also measured. …

This study looks at whether people with multiple myeloma who have responded very well to the drug teclistamab can safely stop taking it after 6-9 months, instead of continuing indefinitely. About 75 participants will stop therapy and be closely monitored, restarting only if their…

This study looks at whether people with multiple myeloma can safely give themselves a standard chemotherapy injection (bortezomib) at home, either by themselves or with a caregiver's help. About 100 adults who have already had at least four injections in a hospital will be taught…

This study is testing two programs that teach emotion-regulation skills to people recently diagnosed with chronic cancer (like metastatic breast, lung, or multiple myeloma). The goal is to see if these programs are practical and helpful for managing anxiety and other psychologica…

This study looks at whether a connected scale can help track the health of 30 people with lymphoma or multiple myeloma who are getting chemotherapy. Patients weigh themselves daily at home for about 7 weeks, and the care team gets alerts if something changes, like sudden weight g…

This study collects medical and genetic information from 520 people with multiple myeloma to better understand why the disease progresses or comes back. Researchers will analyze DNA and RNA from patient samples to find patterns linked to treatment response. The goal is to create …

This study is a registry that collects information from 1,000 patients with blood diseases who receive stem cell transplants at a hospital on the Qinghai-Tibet Plateau. Researchers will track their health, treatments, and costs over time to learn how high altitude affects recover…

This study looks at information already collected from 600 people with multiple myeloma. Researchers will combine genetic, clinical, and imaging data to find patterns and build computer models that may predict how the disease will progress or respond to treatment. No new tests or…

This study is collecting blood, bone marrow, and tissue samples from over 1,000 people with blood cancers like leukemia and myeloma. Researchers will use advanced lab techniques to find unique markers (biomarkers) for each cancer type. The goal is to better understand these disea…