New drug aims to stop nosebleeds in rare blood vessel disorder

NCT ID NCT07601425

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tests an experimental drug called ATV-1601 in people with moderate to severe HHT, a condition that causes frequent nosebleeds and anemia. The trial has two parts: first, participants receive either the drug or a placebo to check safety and effectiveness; then, all eligible participants can receive the drug in an open-label extension. The main goal is to see if ATV-1601 can safely reduce the number and severity of nosebleeds.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

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Other studies related to the condition(s) this trial covers.