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Blood thinners in HHT: a risky balancing act under the microscope

NCT ID NCT05641142

Recruiting now Disease control Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study follows 100 adults with hereditary hemorrhagic telangiectasia (HHT) who start taking blood thinners (anticoagulants or antiplatelets). Researchers compare the three months before treatment to the first three months on treatment, tracking bleeding events, iron levels, and need for transfusions or IV iron. The goal is to see how well patients tolerate these medications in real-world conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
anticoagulant and/or antiplatelet therapy
What this could lead to
If successful, this could help doctors understand how to safely use blood thinners in people with HHT, reducing bleeding risks while managing clotting needs.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all HHT patients, and bleeding risks remain.

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Conditions

The condition(s) this trial relates to.

Epistaxis Hemorrhage hereditary hemorrhagic telangiectasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEREDITARY HEMORRHAGIC TELANGIECTASIA RENDU OSLER DISEASE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HP - Hôpital Ténon

    RECRUITING

    Paris, France

    Contact

    Contact

  • Assistance Publique - Hôpitaux de Marseille

    NOT_YET_RECRUITING

    Marseille, France

    Contact

    Contact

  • CHRU de Lille

    NOT_YET_RECRUITING

    Lille, France

    Contact

    Contact

  • CHRU de Strasbourg

    RECRUITING

    Strasbourg, France

    Contact

    Contact

  • CHU clermont-ferrand

    RECRUITING

    Clermont-Ferrand, France

    Contact

    Contact

  • CHU d'Angers

    RECRUITING

    Angers, France

    Contact

    Contact

  • CHU de Bordeaux

    RECRUITING

    Bordeaux, France

    Contact

    Contact

  • CHU de Caen Normandie

    RECRUITING

    Caen, France

    Contact

    Contact

  • CHU de Dijon

    RECRUITING

    Dijon, France

    Contact

    Contact

  • CHU de Montpellier

    RECRUITING

    Montpellier, France

    Contact

    Contact

  • CHU de Nancy

    RECRUITING

    Nancy, France

    Contact

    Contact

  • CHU de Nantes

    RECRUITING

    Nantes, France

    Contact

    Contact

  • CHU de Nice

    RECRUITING

    Nice, France

    Contact

    Contact

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

    Contact

    Contact

  • CHU de Rennes

    RECRUITING

    Rennes, France

    Contact

    Contact

  • CHU de Toulouse

    NOT_YET_RECRUITING

    Toulouse, France

    Contact

    Contact

  • Hospices Civiles de Lyon

    RECRUITING

    Lyon, France

    Contact

    Contact

  • Hôpital Ambroise Paré

    NOT_YET_RECRUITING

    Boulogne-Billancourt, France

    Contact

    Contact

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