Could a simple ear clip tame brain swelling after a stroke?
NCT ID NCT06799390
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive device that gently stimulates the vagus nerve through the ear can reduce inflammation and brain swelling after a hemorrhagic stroke (intracerebral hemorrhage). The trial enrolls adults with a specific type of brain bleed and compares the active stimulation to a sham (inactive) device. Researchers will measure inflammatory markers in the blood and track changes in brain swelling and neurological function over two weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Auricular Vagus Nerve Stimulation (non-invasive ear stimulation device)
- What this could lead to
- If it works, this could offer a simple, drug-free way to reduce brain swelling and improve recovery after a hemorrhagic stroke.
- What could go wrong
- This is an early-stage study with a small number of participants. The treatment may not reduce inflammation or improve outcomes, and individual results may vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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