Could a simple ear clip tame brain swelling after a stroke?

NCT ID NCT06799390

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive device that gently stimulates the vagus nerve through the ear can reduce inflammation and brain swelling after a hemorrhagic stroke (intracerebral hemorrhage). The trial enrolls adults with a specific type of brain bleed and compares the active stimulation to a sham (inactive) device. Researchers will measure inflammatory markers in the blood and track changes in brain swelling and neurological function over two weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Auricular Vagus Nerve Stimulation (non-invasive ear stimulation device)
What this could lead to
If it works, this could offer a simple, drug-free way to reduce brain swelling and improve recovery after a hemorrhagic stroke.
What could go wrong
This is an early-stage study with a small number of participants. The treatment may not reduce inflammation or improve outcomes, and individual results may vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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