Breakthrough stent aims to fix Hard-to-Treat aortic aneurysms

NCT ID NCT04875429

Recruiting now Disease control Sponsor: Cook Research Incorporated Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device called the Zenith Fenestrated+ Endovascular Graft, used with special stents, to repair aortic aneurysms that involve arteries to the kidneys and other organs. About 105 people with large or fast-growing aneurysms will be enrolled. The goal is to see if the device can be safely placed and prevent serious problems like rupture or kidney failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Zenith Fenestrated+ Endovascular Graft with BeGraft stent system
What this could lead to: If successful, this could offer a less invasive treatment option for complex aortic aneurysms that are hard to treat with standard surgery.
What could go wrong: This is an early-stage study with only 105 participants, so results may not apply to everyone. Risks include serious complications like kidney failure, stroke, or bowel injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm aortic aneurysm cardiovascular disorder vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC ANEURYSM, ABDOMINAL EXTENT IV THORACOABDOMINAL JUXTARENAL AORTIC ANEURYSM PARARENAL ANEURYSM

Contacts and locations

Locations

Barnes Jewish Hospital
RECRUITING

St Louis, Missouri, 63110, United States
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
Carilion Roanoke Memorial Hospital
ACTIVE_NOT_RECRUITING

Roanoke, Virginia, 24014, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Columbia University Irving Medical Center/NY Presbyterian Hospital
RECRUITING

New York, New York, 10032, United States
Dartmouth-Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Edward Hospital
RECRUITING

Naperville, Illinois, 60540, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Endeavor Health Cardiovascular Institute at Glenbrook Hospital
RECRUITING

Glenview, Illinois, 60026, United States
Holston Valley Hospital
RECRUITING

Kingsport, Tennessee, 37660, United States
Hospital of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Loyola University Medical Center
RECRUITING

Maywood, Illinois, 60153, United States
Massachusetts General Hospital
COMPLETED

Boston, Massachusetts, 02114, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Medstar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Memorial Hermann Texas Medical Center/UT Health
RECRUITING

Houston, Texas, 77030, United States
Methodist Hospital of Indiana
RECRUITING

Indianapolis, Indiana, 46202, United States
New York University Langone Medical Center
RECRUITING

New York, New York, 10016, United States
Northwestern Memorial Hospital
RECRUITING

Chicago, Illinois, 60611, United States
St Thomas' Hospital
ACTIVE_NOT_RECRUITING

London, SE1 7EH, United Kingdom
Stanford Hospitals and Clinics
RECRUITING

Stanford, California, 94305, United States
Tampa General Hospital
RECRUITING

Tampa, Florida, 33606, United States
UC San Diego
RECRUITING

La Jolla, California, 92037, United States
University of Alabama Birmingham Hospital
RECRUITING

Birmingham, Alabama, 35294, United States
University of Florida Shands Hospital
RECRUITING

Gainesville, Florida, 32610, United States
University of Maryland
RECRUITING

Baltimore, Maryland, 21201, United States
University of Massachusetts
RECRUITING

Worcester, Massachusetts, 01655, United States
University of Michigan Health System
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
University of Southern California
RECRUITING

Los Angeles, California, 90031, United States
Ut Southwestern
RECRUITING

Dallas, Texas, 75235, United States

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