New device zaps kidney and liver nerves to fight high blood pressure
NCT ID NCT06907147
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 43 times
Summary
This study tests a device that uses radiofrequency energy to calm overactive nerves in the kidney and liver, which may help lower blood pressure. Researchers will enroll 175 adults with uncontrolled hypertension, with or without high cardiovascular risk. The goal is to see if the procedure is safe and can reduce blood pressure over time.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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BayCare Health System Mease Countryside Hospital
RECRUITINGSafety Harbor, Florida, 34695, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Baylor Heart & Vascular Hospital
RECRUITINGDallas, Texas, 75226, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henry Ford Providence Hospital
RECRUITINGSouthfield, Michigan, 48075-4818, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hippokration General Hospital
RECRUITINGAthens, 11527, Greece
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North Mississippi Medical Center
RECRUITINGTupelo, Mississippi, 38801-4934, United States
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orlando Health Heart & Vascular Institute
RECRUITINGOrlando, Florida, 32806, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Piedmont Heart Institute
RECRUITINGAtlanta, Georgia, 30309-1281, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renown Regional Medical Center
RECRUITINGReno, Nevada, 89502, United States
Contact Email: •••••@•••••
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Royal Perth Hospital (Dobney Hypertension Centre)
RECRUITINGPerth, 6000, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford Hospital and Clinics
RECRUITINGStanford, California, 94305, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UT Health East Texas
RECRUITINGTyler, Texas, 75701, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Basel
RECRUITINGBasel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital of Galway
RECRUITINGGalway, H91 YR71, Ireland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universität des Saarlandes
RECRUITINGHomburg, 66421, Germany
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Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virtua Our Lady of Lourdes Hospital
RECRUITINGCamden, New Jersey, 08103, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Multi-Organ Denervation Gemini System (a device that uses radiofrequency energy to disrupt nerve signals in the kidney and liver arteries)
What this could lead to
If it works, this could offer a new, drug-free option to help control high blood pressure, especially for people at high cardiovascular risk.
What could go wrong
This is an early pilot study with only 175 participants, so results may not apply to everyone. The procedure carries risks like artery damage or bleeding, and it is unclear if the blood pressure reduction will be lasting.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.