Disease

Researchers are studying whether a structured care plan called the Indian Asthma Care Bundle (I-ACB) helps adults and children in India manage asthma after a severe attack. The study follows patients discharged from the hospital and compares those who receive the bundle with thos…

This pilot study tests a digital spacer device called aflo™ in children aged 6 to 18 with uncontrolled asthma. The device attaches to a standard inhaler and gives real-time feedback on technique, reminders, and tracks symptoms through a mobile app. Researchers want to see if usin…

This trial tests whether adding a set of ten Pilates-based exercises to standard concussion recovery helps young athletes regain normal movement. Many people recover from concussions using symptom-guided activity, but that approach may leave underlying gait and balance problems u…

This trial asks whether two medications used for endometriosis symptoms, norethindrone acetate and elagolix, affect brain health. Researchers will measure blood flow in the brain and markers of inflammation in 45 women with endometriosis. Participants will be randomly assigned to…

This trial tests whether high-flow nasal cannula (HFNC) oxygen can reduce the risk of hypoxemia, or low blood oxygen, during sedated gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease (COPD). COPD patients often have low oxygen reserves, making them…

This trial tests whether a ventilation strategy based on mechanical power—a measure of energy delivered to the lungs—can reduce postoperative pulmonary complications like pneumonia and collapsed lungs in adults undergoing lung resection surgery. Participants are randomly assigned…

This trial tests an oral drug called avatrombopag in adults with aplastic anemia, a rare condition where the bone marrow fails to make enough blood cells. The study enrolls about 26 people whose disease has not improved with standard treatment, who cannot receive standard treatme…

This study compares two breathing exercises—box breathing and rhythmic breathing—to see which better reduces breathlessness, improves lung function, and enhances sleep quality in adults with mild to moderate asthma. Participants are randomly assigned to one of the two techniques …

This study tests a new drug, linvemastat, for adults with moderate-to-severe asthma that is not fully controlled by standard inhalers. About 135 participants will receive either one of two doses of linvemastat or a placebo, while continuing their usual medications. Over 16 weeks,…

This trial tests a streamlined approach for men at high risk of clinically significant prostate cancer. Under one anesthesia session, doctors perform an MRI-guided biopsy, analyze the tissue immediately with rapid lab tests, and if cancer is confirmed, proceed directly to laparos…

This pilot study tests whether providing medically tailored meals and fresh produce can help people with stage I-III colorectal cancer eat fewer ultra-processed foods. Participants are randomly assigned to receive fully prepared meals, meals plus fresh produce, or meal-planning m…

This phase 2 trial tests a combination of three drugs—sintilimab, ramucirumab, and paclitaxel—in 30 adults with HER2-negative stomach cancer that came back during or within 6 months of finishing adjuvant therapy. The main goal is to see how many patients' tumors shrink significan…

This study tests whether removing a specific type of immune cell (naive T cells) from a donor's stem cell graft can prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the recipient's body. The trial enrolls people with non-malignant blood di…

This Phase 2 trial tests the drug imetelstat in 30 adults with myelodysplastic/myeloproliferative neoplasms (MDS/MPN), a rare blood cancer. The goal is to see if imetelstat can help control the disease and to check for side effects. Participants receive the drug by IV, and the st…

This clinical trial is testing a new approach for people with advanced HER2-negative stomach or gastroesophageal junction cancer that cannot be removed by surgery. The treatment combines two immunotherapy drugs (iparomlimab and tuvonralimab) with standard chemotherapy (SOX) and a…

This study will screen 600 adults aged 55 and older in U.S. communities to find early signs of mild cognitive impairment (MCI). Participants will receive a combination of stem cell therapy, a wearable brain-computer interface device, and wellness coaching to see if these treatmen…

This study tests a traditional Chinese herbal formula (Compound Granules of Hedyotis diffusa) in 20 adults with chronic atrophic gastritis, a condition that can lead to stomach cancer. Participants take the herbal granules for 12 months and are followed for another 12 months. The…

Radiation pneumonitis is a lung inflammation that can appear weeks after radiotherapy for lung cancer, and patients may not link their symptoms to the earlier treatment. Researchers developed a smartphone app called PneumoCheck for patients to use at home, hoping it helps detect …

Researchers at Penn State University are testing three software innovations designed to improve bronchoscopy guidance during lung cancer evaluations. The study enrolls a small number of adults who are already scheduled for a clinical bronchoscopy to examine abnormal lung tissue o…

This trial is testing a new rapid urine test called Jiddu that aims to quickly identify urinary tract infections (UTIs) and determine which antibiotics will work best. The study involves 100 adults with neurogenic bladder who use catheters and suspect they have a UTI. Participant…

Researchers are testing three advanced diffusion MRI sequences to see which one best identifies men who can safely skip a prostate biopsy. The study includes men with suspicious prostate MRI results and those already scheduled for a routine MRI. By comparing these new scans again…

This study tests an artificial intelligence (AI) system called GlaukomAI that analyzes standard eye photos to detect glaucoma, a leading cause of blindness. Researchers will enroll 1,200 participants to see how accurately the AI identifies glaucoma compared to expert doctors. If …

This trial tests whether a new imaging method, using femtosecond laser light and artificial intelligence, can accurately predict high-risk features in lung cancer, such as spread to lymph nodes. Researchers will compare the AI's predictions with actual pathology results from surg…

This observational study will enroll 440 Danish-speaking adults over 50 to see if an artificial intelligence model can detect dementia and mild cognitive impairment from speech recordings. Participants will complete standard cognitive tests and describe a picture while being reco…

This trial tests whether adding a small probe called the Iriscope to standard bronchoscopy improves the diagnosis of lung nodules. Doctors usually guide the biopsy with real-time X-rays, but sometimes they cannot see the nodule directly. The Iriscope slides into the bronchoscope …

This trial tests whether a femtosecond laser imaging technique, combined with artificial intelligence, can accurately distinguish benign from malignant lung tissue in surgical specimens. Researchers will compare the AI-assisted diagnosis against standard pathology results. The st…

This study asks whether an artificial intelligence algorithm can diagnose mycosis fungoides, a rare type of skin lymphoma, from biopsy slides as accurately as certified dermatopathologists. Researchers will compare the AI's sensitivity and specificity against expert readings usin…

This study tests whether a new breathing measurement, called respiratory admittance, can better identify children who have asthma triggered by exercise. Children aged 5 to 16 who are already scheduled for an exercise challenge test will have their breathing measured using this ne…

This pilot study investigates whether a PSMA PET scan, using an injected radiotracer, can detect clinically significant prostate cancer recurrence one year after focal HIFU treatment, compared with the standard MRI. About 30 men with prostate cancer who meet specific criteria wil…

This study tests a new AI framework called Cad-MMFF that combines clinical information, ultrasound, and MRI images to better detect clinically significant prostate cancer. The goal is to see if this approach can reduce unnecessary biopsies and safely limit the use of MRI. The stu…

This study tests whether combining several advanced genetic analysis techniques can find the cause of intellectual disability or neurodevelopmental disorders in people who have already had standard genetic testing with no answer. Participants will have their existing genetic data…

This study is testing whether a new scoring system, called the Fusion CEMEP score, can safely guide prostate biopsy decisions. The goal is to see if men with suspected prostate cancer can skip the extra systematic biopsies and only have targeted biopsies based on MRI findings. Th…

This trial tests whether a special AI system can help doctors diagnose rare diseases more accurately and efficiently. About 1,000 people with suspected rare or hard-to-diagnose conditions will take part. Before seeing the doctor, the AI will gather the patient's medical history a…

This trial explores whether betacyanin, a pigment found in beetroot, can help doctors detect anastomotic leakage — a serious complication where intestinal contents leak after rectal cancer surgery — earlier than current methods. About 120 people undergoing laparoscopic rectal can…

This study investigates whether measuring a protein called neurofilament light chain (NfL) in the blood can help doctors diagnose amyotrophic lateral sclerosis (ALS) more quickly and accurately. ALS is often hard to distinguish from other neurological diseases, leading to delays …

This study explores whether emergency doctors can use a portable ultrasound machine to better assess tissue damage from rattlesnake bites. Current methods rely on physical exams, which may miss early changes. The goal is to see if ultrasound can detect injury earlier and help doc…

This study tests a new imaging tracer called [18F]FAPI-74, which attaches to a protein found on cells in tumors and scarred or inflamed tissue. Researchers want to see if it can show these areas more clearly than current scans. About 770 adults with various cancers or non-cancer …

This trial tests three ways to manage urinary symptoms in women aged 65 and older who have frequent urinary tract infections. Some participants receive antibiotics right away, while others get treatment only after a urine test or a lab culture. The goal is to find out which appro…

This study evaluates whether a quick blood test for NT-pro-BNP, done in a doctor's office, can help diagnose heart failure earlier in rural areas where specialists are scarce. The test is given to people over 60 with symptoms like shortness of breath or swelling. Researchers will…

This study tests an AI-powered imaging device called DeepView to see if it can accurately assess burn injuries on the hands, head, and feet. Researchers will collect images from people with burns in these areas to train and improve the AI system. The goal is to help doctors make …

This study tests an artificial intelligence (AI) prototype designed to quickly evaluate tissue samples taken during a bronchoscopy, a procedure used to diagnose lung cancer. The AI analyzes microscope images of the samples to determine if they are adequate for diagnosis and wheth…

This study explores whether a painless ultrasound technique, called shear wave elastography, can detect early signs of muscle weakness in critically ill patients on breathing machines. About 98 adults will have their nerves scanned on days 1, 4, and 7 in the ICU. The goal is to s…

This study evaluates a portable device that measures lung function using oscillometry—a technique that sends gentle sound waves into the lungs—to diagnose chronic respiratory diseases like COPD, asthma, and bronchiectasis. Researchers will enroll about 4,000 adults across 50 cent…

This study tests whether an artificial intelligence (AI) tool can help doctors better diagnose rare diseases. About 150 doctors will either use the AI or rely on standard methods to diagnose real patient cases. The goal is to see if AI improves accuracy and speed, which could lea…

This study tests whether AI-powered decision trees can help general practitioners better diagnose and manage allergies. About 600 patients with suspected allergies will be enrolled, and doctors will use an app that suggests next steps based on symptoms. The goal is to see if this…

This study tests a workshop led by peers and a Black GP to encourage Black men aged 45 and over to talk to their doctor about prostate cancer risk and get a PSA test. About 300 men from three UK regions will take part. Half attend the workshop right away, the other half wait six …

This study will collect cough sounds, breath sounds, and symptom questionnaires from 1,400 children with respiratory symptoms like cough or fever. Researchers will use this data to build a computer model that can help diagnose conditions like asthma and pneumonia. The goal is to …

This study will test a new blood test that looks for DNA changes to detect ovarian cancer, especially in early stages. Researchers will compare test results from 1,000 women with and without ovarian cancer to see how accurate it is. If it works well, it could lead to a simple scr…

This study looks for early signs of a heart condition called cardiac amyloidosis in people who have had carpal tunnel surgery on both hands. Researchers will use a special heart scan to check for abnormal protein buildup. The goal is to find the disease earlier so treatment can s…

This study is testing whether a simple, 1-minute heart recording (ECG) analyzed by a computer can help detect pulmonary embolism, a serious blood clot in the lungs. Researchers will enroll 500 adults who need to be checked for this condition. The goal is to see if this quick, non…

This study will test a new, non-invasive bedside scan (3D-EIT) to see if it can accurately diagnose and monitor pulmonary embolism (blood clots in the lungs) without using radiation. About 115 adults with and without clots will participate. The goal is to provide a safer, easier …

This study is testing a new, easy way to diagnose asthma and COPD using a handheld device that measures carbon dioxide in a person's breath. Instead of the current uncomfortable and time-consuming lung tests, participants simply breathe normally into the device for 75 seconds. Th…

This study will test a new, disposable freezing catheter (Celsio) in 30 people who need a lung procedure. The catheter uses extreme cold to help diagnose or treat conditions like lung cancer and interstitial lung disease. Unlike current devices, it does not need a bulky console o…

This study will collect thousands of photos of mouth lesions from patients seen over 50 years at a French hospital. Experts will review each photo to confirm the diagnosis. Researchers will then use these images and patient data to train an AI system to automatically identify can…

This study looks at how quickly the optic nerve sheath shrinks after starting steroids in people with giant cell arteritis, a condition that can cause blindness. Researchers will use eye ultrasounds and blood tests over two months in 60 newly diagnosed patients. The goal is to fi…

This early study tests a new radioactive tracer called 64Cu-GRIP B that targets a protein released by immune cells during heart inflammation. Researchers will scan 10 people with acute myocarditis to see if the tracer can clearly highlight inflamed areas of the heart. If it works…

This study aims to validate an Italian version of a widely used questionnaire for screening periodontitis (gum disease). Researchers will also develop an enhanced version with additional questions and test how accurately it identifies people with the condition. About 495 adults a…

This study tests whether new, easier-to-use diagnostic tests for tuberculosis (TB) can help find more cases in Indonesia. About 40,000 people with TB symptoms will take part. Some clinics will use the new tests, while others will use standard methods. The goal is to see if the ne…

This study explores whether eye-tracking technology can help screen for autism in children aged 4 to 10. Researchers will compare how children with and without autism look at faces and other social cues. The goal is to develop a simpler diagnostic tool that doesn't require strong…

This study looks at whether low-dose CT scans can help find lung cancer early in people aged 40 to 80 who have never smoked. About 2,500 participants will fill out questionnaires, give blood and urine samples, and have lung function tests and CT scans. Researchers will track how …

This study will test whether a new type of PET scan (18F-FAPI) can more accurately detect lung cancer and help predict patient outcomes. About 120 adults already diagnosed with lung cancer will receive the scan. The goal is to see if this imaging method is better than current tec…

This study tests whether analyzing chemicals in a person's breath can quickly identify serious respiratory infections like COVID-19, flu, and Legionella in hospitalized patients. Researchers will collect breath samples from 777 adults using a simple bag, then analyze them in a la…

This study tests whether an artificial intelligence system can analyze standard heart tracings (ECGs) to detect pulmonary hypertension—a serious but often unnoticed condition—before surgery. About 1,380 adults scheduled for non-cardiac surgery will be randomly assigned to get the…

This study explores a new way to diagnose gastric cancer by analyzing tiny particles called extracellular vesicles found in stomach fluid. Researchers will collect stomach fluid from 100 patients undergoing gastroscopy and use a special sensor to detect cancer-related changes. Th…

This study tests a new, less invasive way to screen for stomach cancer using a magnetic-guided video capsule that patients swallow. The capsule is steered by a robot and uses AI to check the stomach for suspicious spots. Researchers will compare its accuracy to standard endoscopy…

This study compares a new robot-assisted system to the standard manual method for taking a tissue sample (biopsy) from a lung nodule. The goal is to see if the robot is as safe and effective at diagnosing lung cancer or other conditions. About 158 adults with suspicious lung nodu…

This study is developing a new, non-invasive saliva test that uses artificial intelligence to detect gum disease (periodontitis) early. Researchers will collect saliva from 200 adults—some with gum disease and some healthy—and analyze it with a special sensor. The goal is to see …

This study is developing a new blood test that combines quantum sensors and artificial intelligence to detect prostate cancer. Researchers will analyze DNA fragments in blood samples from 1100 men to train an AI model. The goal is to create a non-invasive, accurate diagnostic too…

This study will test a new blood test that looks for tiny molecules called miRNAs to detect HCMV infection earlier in people who have received a stem cell transplant. The standard DNA test can miss early signs, so researchers hope this new method will give doctors a head start. A…

This study will enroll 2,000 adults to see if non-invasive methods like smartphone photos, dental X-rays, and questionnaires can accurately detect gum disease compared to a standard clinical exam. Researchers will use artificial intelligence to analyze the images and combine data…

This early-stage trial tests whether a daily supplement called SAMe can help prevent colorectal polyps (precursors to colon cancer) in 18 adults who have already had surgery for early-stage colon cancer. Participants will take SAMe for up to a year while researchers monitor for s…

This study tests whether placing soft foam dressings on the skin before heart surgery can prevent pressure injuries (bedsores). About 80 adults having long heart surgeries will be enrolled. Researchers will check for new skin injuries after surgery and track how severe they are. …

Endometriosis causes chronic pelvic pain and painful periods, and current treatments do not work for everyone. Researchers are testing whether desloratadine, an antihistamine usually taken for allergies, can reduce pain and improve quality of life. The trial enrolls 60 women aged…

Researchers compare two surgical methods for removing an inflamed appendix in obese patients: laparoscopic (keyhole) surgery and traditional open surgery. The trial enrolls 166 obese adults with acute appendicitis, randomly assigning each to one of the two procedures. The main go…

This trial tests a virtual mind-body group program for female survivors of colorectal and anal cancer who experience sexual well-being challenges. Participants join weekly group sessions with other survivors to learn coping skills for physical changes, social factors, and thought…

This study tests if giving a long-lasting numbing medicine in two different places around the ribs and chest wall can reduce pain and the need for strong painkillers after robotic lung surgery. About 300 adults having this surgery will be randomly assigned to receive the numbing …

This study will compare two sedative drugs, remimazolam and dexmedetomidine, in 60 adults with obstructive sleep apnea undergoing drug-induced sleep endoscopy. The goal is to see which drug provides more stable sedation, fewer side effects like low heart rate or low blood pressur…

This study tests a digital tool called RECapp that helps patients recover after surgery for esophageal or stomach cancer. The app lets patients track symptoms, get personalized self-care advice, and know when to contact their healthcare team. 250 adults in Sweden will use the app…

Shortness of breath, or dyspnea, affects most lung cancer patients and often persists despite standard treatments. This pilot study tests a stepped-care behavioral intervention called INSPIRE, which starts with brief coping skills and adds more intensive psychological support onl…

This study tests whether weekly group music therapy sessions can improve wellbeing, social connection, and relationship quality for people living with dementia and their informal carers. Over 10 weeks, participants attend sessions led by a registered music therapist at a day cent…

This study tests whether doing simple mental arithmetic before walking can improve gait speed and balance in people who have had a stroke. Seventeen participants will either solve math problems or watch a blank screen before walking. The goal is to see if this 'cognitive priming'…

This pilot study tests whether anakinra, a drug that reduces inflammation, can help people with moderate asthma attacks. 60 adults at high risk for asthma attacks will either receive anakinra or a placebo at home when they feel an attack starting. The study will check if this app…

This study tests whether spending time in nature can help people recover faster from a concussion. 24 participants aged 14-35 who recently had a concussion will either do guided awareness exercises in a natural setting or indoors. Researchers will track symptoms, thinking speed, …

This phase 2 trial tests whether adding a steroid eye drop (fluorometholone) to standard antibiotic treatment improves vision at 3 months in people with bacterial corneal ulcers. About 174 adults with mild to severe ulcers will be randomly assigned to get either the steroid plus …

This study compares 3D-printed hand orthoses (braces) to traditional custom-made ones in 100 adults with chronic hand conditions from nerve, muscle, or bone issues. The goal is to see if the 3D-printed versions work just as well for daily activities, are more satisfying, and cost…

This study tests whether wearing a special LED vest for 20 minutes twice a week can improve lung function and exercise ability in children aged 6 to 17 with mild to moderate asthma. The vest uses light to reduce inflammation without heat. Half the children will get the active ves…

This study tests whether acupuncture can help people with mild-to-moderate chronic asthma breathe better and feel less anxious or depressed. 180 adults will be randomly assigned to real acupuncture, fake acupuncture, or usual care. The main goal is to see if real acupuncture impr…

This study tests whether a home-based exercise program can help people with gastrointestinal or lung cancer handle chemotherapy better. Up to 120 participants will be randomly assigned to either an aerobic and resistance exercise group or a stretching group. All activities are do…

This study looks at whether a fast, bedside test (SPOTFIRE) can help doctors better treat children with respiratory infections in the emergency department. About 720 children aged 2 months to 18 years will be randomly assigned to either get the rapid test or standard care. The go…

This pilot study tests whether combining non-invasive brain stimulation (over the cerebellum) with spinal cord stimulation can improve arm and hand function in people with chronic cervical spinal cord injury. Twenty-four participants will receive either both stimulations, spinal …

This study tests a new digital program designed to help people with moderate to severe asthma manage breathlessness and increase physical activity. Researchers will compare the program to usual care in 300 adults. The goal is to see if the program improves quality of life and ast…

This study tests if a 4-week prehabilitation program delivered through WhatsApp can help adults with colorectal cancer prepare for and recover from elective surgery. The program includes educational information, diet advice, exercises, and psychological podcasts. Researchers will…

This study compares two types of inhalers—pressurized metered dose inhalers (pMDI) and dry powder inhalers (DPI)—to see which delivers asthma medication more effectively. Researchers will enroll 210 patients with uncontrolled asthma and measure changes in symptom control after 8 …

This early-stage trial tests a single oral dose of ADO-5030 in 36 adults with mild-to-moderate asthma. Researchers will check safety and how the drug affects breathing during a controlled airway challenge. The goal is to gather initial data, not to prove the drug works yet.

This study tests whether using a lung perfusion PET/CT scan to guide radiation planning can reduce lung injury compared to standard anatomical planning. About 418 adults with lung tumors receiving stereotactic body radiotherapy (SBRT) will be randomly assigned to one of the two p…

This study tests whether wearing a head-cooling device for 28 days can help women ages 18-27 recover from a concussion. Researchers will measure changes in thinking, sleep, mood, and brain inflammation. The goal is to see if cooling the brain speeds up recovery and eases symptoms…

This study compares two types of heart valve surgery: a newer, less invasive method through a small cut on the right side of the chest versus the traditional method through a cut down the middle of the chest. Researchers will measure how quickly patients recover, including time o…

This study tests whether teaching patients how to move safely after lumbar stabilization surgery—using virtual reality videos and brochures before the operation—can reduce pain, anxiety, fear of movement, and fear of falling, and improve mobility. Sixty adults having their first …

This study tests a 'peri-habilitation' program for 30 gastric cancer patients aged 65 and older. Participants receive nutrition education and protein-enriched soy milk for two weeks before surgery, plus exercise training and continued nutrition support for three weeks after leavi…

This trial tests whether a mobile health (mHealth) program can improve quality of life for colorectal cancer survivors who have finished active treatment. About 210 Vietnamese-speaking adults will either use the app daily and receive biweekly phone calls for 3 months, or get usua…

Researchers are testing whether specialized tests of airway inflammation and lung abnormalities can predict asthma remission and relapse better than standard clinical assessments. The trial enrolls adults with severe asthma who are starting biologic therapy. Participants are rand…

This study will compare two different devices that measure pressure and flow during swallowing in 25 healthy adults. The goal is to see how differences in the devices affect the measurements, which could help standardize the diagnosis of swallowing disorders (dysphagia). Particip…

This study aims to create a large collection of lung and airway tissue samples from people with COPD, asthma, and healthy volunteers. Researchers will gather samples through bronchoscopy, sputum, nasal brushing, and blood draws during routine procedures or surgeries. The goal is …

ALS is a progressive nerve disease with no simple test for early diagnosis or tracking. This study is collecting blood samples and medical data from 200 people with ALS to look for patterns in proteins, genes, and immune markers. The goal is to build a biomarker panel that could …

This pilot trial tests whether a risk calculator designed for Nigerian men can help primary care providers better identify those with clinically significant prostate cancer. Researchers will train healthcare workers at community hospitals and then support them in using the tool f…

This study tests a simple tool—short information cards on a mobile phone—to help pregnant people feel more confident when deciding about prenatal genetic screening. About 1,400 participants will use the cards before their first doctor visit, or receive usual care. Researchers wil…

Superficial vein thrombosis (SVT) is a painful but usually harmless blood clot just under the skin. However, about 4% of people develop more serious clots in deep veins or lungs. Current guidelines recommend ultrasound scans to decide if blood thinners are needed, but scans are o…

This study looks at whether a painless ultrasound scan of the sciatic nerve and a blood test for a specific protein can help detect diabetic peripheral neuropathy (nerve damage) earlier than current methods. Researchers will measure nerve size and blood flow in 120 people with ty…

This study will follow 200 people with suspected or confirmed cardiac amyloidosis, a condition where abnormal proteins build up in the heart and cause heart failure. Over two years, participants will undergo heart MRI scans, exercise tests, and blood work at regular visits. The g…

This observational study will enroll 300 people with suspected lung lesions to see if 3D ultrasound can measure them as accurately as CT scans. Participants will undergo both ultrasound and CT imaging, and researchers will compare the results. If the 3D ultrasound works well, it …

This study watches anesthesia residents as they place epidural catheters in 440 patients having elective surgery. It compares two common techniques—loss of resistance and hanging drop—to see which leads to more first-attempt successes and fewer complications like accidental dural…

This study looks at whether a specially trained physical therapist can diagnose jaw disorders (like TMJ) as accurately as an oral surgeon. 70 people with jaw pain will be checked by both a physical therapist and a surgeon, and their diagnoses will be compared. The goal is to see …

This study will use a digital platform with game-like tasks to measure thinking and reading skills in 300 children aged 3-11 who are suspected of having a neurodevelopmental disorder. The goal is to create detailed cognitive profiles before a formal diagnosis, helping to identify…

This observational study will collect pulp tissue from 1,200 adults during routine dental procedures like root canals or extractions. Researchers will analyze the tissue to understand the immune and inflammatory response at the molecular level. The goal is to see if current diagn…

This study looks at chronic sinusitis with nasal polyps, a condition causing long-term nasal congestion and breathing problems. Researchers will measure inflammation markers and examine nasal tissue from 10 adults using a steroid spray (budesonide). The goal is to better understa…

This study will enroll 1,000 adults at high risk for prediabetes to see if continuous glucose monitors (CGMs) combined with artificial intelligence can detect the condition earlier and more accurately than current tests. Participants will wear a CGM and provide other health data.…

This study follows 60 adults with hand or upper limb injuries to see if improvements in the first weeks of rehab can predict function months later. A digital tool created by a therapist tracks progress and patient feedback. The goal is to help clinicians make better, data-driven …

This study will test if a simple, low-intensity cycling exercise combined with a handheld monitor can predict serious complications in lung cancer patients before surgery or other treatments. Researchers will include 500 adults with suspected lung cancer. The goal is to make risk…

The SIRENA study will follow 300 children and adults who have tested positive for islet autoantibodies, which are early markers of type 1 diabetes. Over up to 10 years, researchers will track how their blood sugar, immune system, and metabolism change. The goal is to better predi…

This study will test whether a training program based on Acceptance and Commitment Therapy (ACT) can help university students in Mexicali improve their eating behaviors, reduce anxiety and depression, and change brain activity related to attention and control. Thirty students wil…

This study looks at whether adding a short story to the beginning of an online health questionnaire makes people more likely to complete it. Researchers will invite 500 adults from an existing health study to fill out a survey about physical activity. Half will see a standard sur…

This study watches 300 ICU patients to see how often blood clots caused by catheters remain in the vein after the catheter is taken out. Researchers will track risk factors and whether these clots lead to serious issues like lung clots or long-term vein damage. No new treatments …

This study is testing a co-created digital health literacy tool designed to help people better understand prostate cancer prevention and care. Researchers will enroll 3,100 adults aged 40 and older, including patients, caregivers, and healthcare professionals, across six European…

This study will ask 460 teenagers with asthma in China to fill out questionnaires about their asthma control, anxiety, depression, and self-care skills. The goal is to understand how mental health and disease management are connected in this age group. No new treatments or medica…

This study tests whether a prepackaged low-residue diet (Colobox) helps clean the colon better than just following oral and written instructions before a colonoscopy. Around 230 adults will be randomly assigned to one of two diet plans for 24 hours before the procedure. The goal …

This study looks at how whole body vibration from military or civilian jobs (like flying helicopters or driving trucks) affects the spine health of 112 veterans aged 20-45. Researchers will use advanced MRI scans to see changes in the discs and bones of the spine, both right afte…

This study looks at whether tongue and facial images can help doctors understand psoriasis better. Researchers will collect photos and lab data from 450 people with and without psoriasis. The goal is to find patterns that link Traditional Chinese Medicine signs to blood tests and…

This study aims to discover rare genetic changes that make people more likely to develop cancer. Researchers will collect blood, saliva, and tumor samples from 100 participants who have had multiple cancers or have a strong family history of cancer, along with their relatives. By…

This study will enroll 300 pregnant women to see if continuous glucose monitors (CGMs) and AI tools can diagnose gestational diabetes earlier and more accurately than current methods. Researchers will also look at how CGM data relates to health outcomes for mothers and babies. Th…

This study looks at whether training general practitioners to better monitor and manage kidney health can slow the loss of kidney function in people with type 2 diabetes. About 360 patients aged 50 and older with early kidney problems will take part. Doctors in the intervention g…

This study will analyze genetic data from 100,000 people to see if variations in aldehyde-metabolizing genes (ADH1B and ALDH family) are linked to lung cancer risk, especially in people who have never smoked. The goal is to understand how these genes might influence the developme…

This study is about translating and testing a questionnaire called QoR-15 for Romanian-speaking patients. The questionnaire measures how well people recover after surgery and anesthesia. Researchers will ask 250 adults to fill it out to make sure it works correctly in Romanian. T…

This study will follow 300 older adults (70+) who have mild cognitive impairment (MCI) for one year to see if feeling lonely makes them more likely to develop dementia. Researchers will track who progresses from MCI to dementia and compare loneliness levels. The goal is to unders…

This study looks at how low body temperature during lung cancer surgery (using a tiny camera) affects pain and complications after the operation. About 144 adults having this surgery will have their temperature tracked continuously. The goal is to understand if getting cold durin…

This study will measure specific immune cells in the blood of 200 non-small cell lung cancer patients before and after surgery. The goal is to see if these markers can help predict if the cancer will come back or how long patients will live. Participants must have early-stage lun…