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Breath sniff test could spot COVID and flu in hospital patients

NCT ID NCT07352462

Not yet recruiting Diagnosis Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether analyzing chemicals in a person's breath can quickly identify serious respiratory infections like COVID-19, flu, and Legionella in hospitalized patients. Researchers will collect breath samples from 777 adults using a simple bag, then analyze them in a lab. The goal is to see if this painless, non-invasive method can accurately tell bacterial from viral infections, potentially speeding up diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Volatile organic compounds (VOC) analysis in exhaled breath using GC-MS
What this could lead to
If successful, this could lead to a quick, painless breath test to diagnose serious respiratory infections, helping doctors choose the right treatment faster.
What could go wrong
This is an early observational study, not a treatment trial. The breath test may not be accurate enough to replace current diagnostic methods, and results may vary across different infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

COVID-19 disease influenza legionellosis Legionnaires' disease respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19 INFLUENZA VIRUS INFECTION LEGIONELLA PNEUMOPHILA INFECTIONS RESPIRATORY INFECTIONS

Contacts and locations

Locations

  • Emergency department (Hôpital de la Croix-Rousse, Hospices Civils de Lyon)

    Lyon, 69004, France

  • Infectious Disease Service of Hôpital de la Croix-Rousse (Hospices Civils de Lyon)

    Lyon, 69004, France

  • Intensive Care Unit of Hôpital Lyon Sud (Hospices Civils de Lyon)

    Lyon, 69004, France

  • Intensive Care Unit of Hôpital de la Croix-Rousse (Hospices Civils de Lyon)

    Lyon, 69004, France

  • Internal Medecine Unit of Hôpital de la Croix-Rousse (Hospices Civils de Lyon)

    Lyon, 69004, France

  • National reference center for respiratory viruses (Hôpital de la Croix-Rousse, Hospices Civils de Lyon)

    Lyon, 69004, France

  • Pneumology Unit of Hôpital de la Croix-Rousse (Hospices Civils de Lyon)

    Lyon, 69004, France

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