Single-session strategy could transform high-risk prostate cancer care

NCT ID NCT07709338

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial tests a streamlined approach for men at high risk of clinically significant prostate cancer. Under one anesthesia session, doctors perform an MRI-guided biopsy, analyze the tissue immediately with rapid lab tests, and if cancer is confirmed, proceed directly to laparoscopic prostatectomy. The goal is to see if this single-stage pathway is as accurate and safe as the usual multi-step process, potentially saving time and reducing patient burden.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a streamlined diagnostic-surgical pathway combining MRI/ultrasound fusion targeted biopsy, intraoperative frozen section and rapid immunohistochemistry, and immediate laparoscopic radical prostatectomy
What this could lead to
If successful, this approach could allow men with high-risk prostate cancer to receive diagnosis and treatment in a single session, reducing delays and the need for a separate biopsy procedure.
What could go wrong
This is an early-stage study with only 150 participants, so results may not apply to all patients. The rapid pathology may not always match standard lab results, and same-session surgery carries risks like infection or bleeding.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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