Could a steroid eye drop help heal corneal ulcers faster?

NCT ID NCT07308938

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether adding a steroid eye drop (fluorometholone) to standard antibiotic treatment improves vision at 3 months in people with bacterial corneal ulcers. About 174 adults with mild to severe ulcers will be randomly assigned to get either the steroid plus antibiotics or antibiotics alone. The study also tracks healing time, eye pressure, and complications.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
fluorometholone eye drops
What this could lead to
If it works, this could lead to a standard treatment that improves vision and speeds healing for people with bacterial corneal ulcers.
What could go wrong
This is a small, early-phase trial, so results may not apply to everyone. Adding steroids to an infection could sometimes worsen the infection or cause side effects like increased eye pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UPMC Vision Institute

    Pittsburgh, Pennsylvania, 15219, United States

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Other studies related to the condition(s) this trial covers.