Gene variants may raise lung cancer risk in Never-Smokers

NCT ID NCT07273279

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study will analyze genetic data from 100,000 people to see if variations in aldehyde-metabolizing genes (ADH1B and ALDH family) are linked to lung cancer risk, especially in people who have never smoked. The goal is to understand how these genes might influence the development of lung cancer and its subtypes. No treatment is being tested; this is purely an observational genetic study.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could help identify people with higher genetic risk for lung cancer, potentially leading to better screening or prevention strategies.
What could go wrong
This is an observational study that only looks at genetic associations, not a treatment trial. It may not find clear links, and results may not apply to all populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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