Could a nebulized cocktail make lung scopes less Cough-Inducing?

NCT ID NCT07743333

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial tests whether adding nebulized ketamine to lidocaine before a fiberoptic bronchoscopy reduces coughing and discomfort compared to lidocaine alone or standard spray. About 134 adults scheduled for bronchoscopy will receive one of three premedication approaches. The study tracks cough severity, patient tolerance, satisfaction, and safety, including blood pressure and oxygen levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Nebulized lidocaine and ketamine
What this could lead to
If effective, this combination could make bronchoscopy more comfortable and safer, reducing coughing and improving patient tolerance during the procedure.
What could go wrong
This is a single-center trial with a modest number of participants, and the added benefit of ketamine may be small or come with side effects like sedation or blood pressure changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alexandria University Faculty of Medicine

    Alexandria, Alexandria Governorate, 21526, Egypt

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