LUNG ADENOCARCINOMA

This early-phase study is testing a new type of cell therapy for people with advanced solid tumors, including melanoma, that have spread and are not responding to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack c…

This early safety study is testing whether a diabetes drug called dapagliflozin is safe to give to people with early-stage lung cancer before they have surgery. Researchers want to see if taking the pill for 30 days before the operation helps make the surgery more effective by po…

This study is testing a new combination treatment for patients with advanced, inoperable lung cancer who have no other options left. It combines a very precise, high-dose radiation shot to only part of the tumor with a drug that helps the immune system fight cancer. The goal is t…

This study is testing a new oral drug called TNG260, given alone and with the immunotherapy pembrolizumab, for people with advanced solid tumors that have a specific genetic change (STK11 mutation). The main goals are to find a safe and effective dose and to see if the treatment …

This large Ohio study aims to see if using advanced genetic and immune testing on tumors can help doctors choose more effective, personalized treatments for people with advanced lung cancer. It will compare this approach to usual care in over 2,100 patients. The study also includ…

This study is testing if adding a tumor-freezing procedure (cryoablation) to standard drug therapy helps people with advanced lung cancer live longer. It will enroll 214 patients who will be randomly assigned to receive either the standard drugs alone or the drugs plus the freezi…

This study is testing whether adding an experimental drug called TRC102 to standard treatment helps people with stage III non-squamous non-small cell lung cancer live longer without their cancer getting worse. About 42 participants will receive either the standard treatment (chem…

This study is testing a new, experimental cancer drug called AZD5335 to see if it is safe and if it can help control advanced cancers. It will be given alone and in combination with other cancer drugs to adults with ovarian, lung, or endometrial cancers that have progressed despi…

This study is testing if following a special low-carb, high-fat (ketogenic) diet for one week before a PET scan can help doctors more accurately spot a specific type of lung cancer. It will involve about 30 adults who have a suspicious lung nodule. The goal is to see if this diet…

This study aims to find new markers in the fluid that builds up around the lungs (pleural effusion) to help doctors better diagnose lung adenocarcinoma. Researchers will compare fluid samples from 100 patients with and without this type of lung cancer. The goal is to develop a mo…

This study is testing a new type of PET scan to see if it can detect lung cancer earlier and more accurately. Researchers will give 60 participants a special radioactive glucose tracer and then perform a PET/CT scan. The goal is to see if this new method is safe and works better …

This study is testing whether yoga and mindfulness training can help improve the quality of life for people who have survived lung, colon, or non-Hodgkin's lymphoma cancer. Researchers will enroll 100 adult survivors who finished their main cancer treatments at least six months a…

This study is testing whether weekly phone calls from a trained support worker can improve the quality of life for Veterans with lung cancer. About 194 Veterans will be randomly assigned to either receive these support calls in addition to their usual care, or to receive only the…