New brain radiation combo aims to fight tumors and save memory
NCT ID NCT07481786
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This phase 3 trial tests two ways to treat lung cancer that has spread to the brain. One group gets targeted radiation to each tumor plus a drug (bevacizumab) that starves tumors of blood. The other group gets whole-brain radiation that tries to avoid the memory centers. The study will see which approach better controls brain tumors and protects thinking skills. About 220 adults with lung adenocarcinoma and multiple brain metastases are being recruited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bevacizumab (a drug that blocks blood vessel growth to tumors)
What this could lead to
If successful, this could offer a more targeted brain radiation approach that better controls tumors while preserving memory and thinking skills.
What could go wrong
This is an early-stage Phase 3 trial, so results are not yet known. The experimental group adds a drug (bevacizumab) that carries risks like bleeding or high blood pressure, and the benefit over standard whole-brain radiation is unproven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sun yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400016, China
Contact Email: •••••@•••••
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The First Affiliated Hospital of Guangzhou University of Chinese Medicine
RECRUITINGGuangzhou, Guangdong, 510405, China
Contact Phone: •••-•••-•••• Email: •••••@•••••