Metastatic malignant neoplasm
MONDO:0024880A malignant tumor that has spread from its original (primary) site of growth to another site close to or distant from the primary site.
Also known as: malignant metastatic neoplasm, metastatic cancer, metastatic malignant neoplasm, metastatic neoplasm, malignant
3809 clinical trials for this condition and its sub-types, 748 tagged with Metastatic malignant neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Metastatic malignant neoplasm
-
Metastatic malignant neoplasm in the brain 267 trials
-
Metastatic carcinoma 22 trials · 168 incl. sub-types
4 sub-types
- Metastatic carcinoma in the bone 107 trials
- Metastatic squamous cell carcinoma 39 trials
- Krukenberg carcinoma 1 trial
- Metastatic carcinoma in the adrenal medulla 0 trials
-
Neoplastic meningitis 82 trials
-
Metastasis from malignant tumor of colon 27 trials
-
New combo therapy aims to stop bone cancer from coming back
Disease control CompletedThis study tests whether giving a precise, high-dose radiation treatment (SBRT) to bone tumors before surgery is safe and can prevent the cancer from returning. About 39 adults with cancer that has spread to their bones and who need surgery to stabilize a fracture risk will recei…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Sep 21, 2026 16:00 UTC
-
New drug combo targets Hard-to-Treat cancers
Disease control CompletedThis study tests two experimental drugs, ERAS-007 and ERAS-601, in people with advanced solid tumors that have not responded to standard treatments. The drugs are taken orally and aim to block signals that help cancer grow. The trial will first find safe doses and then check if t…
Phase 1/2 • Sponsor: Erasca, Inc. • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
-
New drug combo targets Hard-to-Treat cancers in early trial
Disease control CompletedThis early-phase study tests a new drug called ERAS-601, alone or with other cancer treatments, in adults with advanced solid tumors that have not responded to standard therapies. The main goals are to find safe doses and check for side effects. About 90 participants will take pa…
Phase 1 • Sponsor: Erasca, Inc. • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
-
New drug cocktail targets Hard-to-Treat cancers
Disease control CompletedThis early-stage trial is testing a new drug called tuvusertib, given together with either lartesertib or avelumab, in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the best dose, and see how the body pr…
Phase 1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
-
Drug combo shows promise for tough head and neck cancers
Disease control CompletedThis phase 2 study tested two drugs—durvalumab and cetuximab—together in 35 people with head and neck cancer that had come back or spread and was no longer responding to standard treatments. The goal was to see if the combination could shrink tumors. The study is complete, and re…
Phase 2 • Sponsor: University of Cincinnati • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
-
Can a new antibody help the immune system fight Hard-to-Treat tumors?
Disease control CompletedThis trial tests an experimental drug called SNS-101, which targets a protein called VISTA that may help tumors evade the immune system. Researchers give SNS-101 alone or with another immunotherapy, cemiplimab, to adults with advanced solid tumors that have not responded to stand…
Phase 1/2 • Sponsor: Sensei Biotherapeutics, Inc. • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
-
New drug combo targets Hard-to-Treat cancers
Disease control CompletedThis early-phase study tests an experimental drug called MK-6837, given alone or with another drug (pembrolizumab), in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug sh…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
-
New drug combo shows promise in halting advanced cancers
Disease control CompletedThis early-phase trial tested a combination of two drugs, vandetanib and everolimus, in 151 people with advanced or metastatic cancer that had stopped responding to standard treatments. The goal was to find the safest dose and see if the combination could slow or stop cancer grow…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
-
New combo therapy aims to shrink Hard-to-Treat neuroendocrine liver tumors
Disease control CompletedThis phase 2 pilot study tests whether combining the immunotherapy drug pembrolizumab (Keytruda) with liver-directed treatments (like embolization or radiation) or peptide receptor radionuclide therapy (PRRT) can shrink tumors in people with well-differentiated neuroendocrine tum…
Phase 2 • Sponsor: Nicholas Fidelman, MD • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
-
New drug combo shows promise in early cancer trial
Disease control CompletedThis early-stage study tests a new drug called WTX-124, given alone or with another drug (pembrolizumab), in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. About 150 adults with certain…
Phase 1 • Sponsor: Werewolf Therapeutics, Inc. • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
-
New drug candidate CBX-12 tested in patients with Hard-to-Treat cancers
Disease control CompletedThis study tested an experimental drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, breast, or colon cancer) that had stopped responding to standard therapies. The main goals were to check the drug's safety, find the best dose, and see if it could sh…
Phase 1/2 • Sponsor: Cybrexa Therapeutics • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
-
Can a daily dose of velcade outsmart solid tumors?
Disease control CompletedThis trial is testing whether giving the cancer drug bortezomib (Velcade) every day, instead of the usual weekly or biweekly schedule, is safe and might work better against advanced or metastatic solid tumors. The study enrolls adults with solid tumors for whom standard treatment…
Phase 1 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
-
New drug cocktail targets tough cancers in early trial
Disease control CompletedThis early-phase study tested a combination of two drugs, temsirolimus and cetuximab, in 45 adults with advanced or metastatic solid tumors that had not responded to standard treatments. The goal was to check safety and see if blocking two cancer pathways at once could slow tumor…
Phase 1 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
-
Rollover trial tests continued sitravatinib combo for advanced cancers
Disease control CompletedThis study looked at the safety and effectiveness of continuing sitravatinib, a targeted cancer drug, either alone or combined with other therapies like nivolumab or pembrolizumab, in people with advanced or metastatic solid tumors. It enrolled 52 patients who were already benefi…
Phase 2/3 • Sponsor: Mirati Therapeutics Inc. • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
-
Gut radiation may revive immunotherapy in resistant cancers
Disease control CompletedThis phase 2 trial investigates whether a single, low dose of radiation to the small intestine can help the immune system recognize and attack tumors again in people with advanced solid cancers that have stopped responding to immunotherapy. Participants receive 1Gy of radiation t…
Phase 2 • Sponsor: Chuangzhen Chen • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
-
Experimental pill takes on advanced cancers alongside immunotherapy
Disease control CompletedThis early-phase trial tests an experimental oral drug, MK-6598, both by itself and in combination with the immunotherapy pembrolizumab (Keytruda) in adults with advanced or metastatic solid tumors. The main goals are to check safety, find the right dose, and see early signs of t…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
-
New drug PEP-010 shows promise in early cancer trial
Disease control CompletedThis early-phase trial tests a new drug called PEP-010 in people with advanced solid tumors that have spread. The study checks if PEP-010 is safe alone or with chemotherapy (paclitaxel or gemcitabine). About 57 adults with metastatic pancreatic, ovarian, or other solid cancers wi…
Early phase 1 • Sponsor: Institut Curie • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
-
Zapping tumors with precision radiation may help control limited metastatic breast cancer
Disease control CompletedThis study looked at whether adding focused radiation (SBRT) or surgery to standard treatments like chemo or hormone therapy helps people with breast cancer that has spread to just one or two places. 129 participants were randomly assigned to get standard care alone or standard c…
Phase 2/3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
-
Double immunotherapy plus liver blockade targets eye cancer that spreads
Disease control CompletedThis trial investigates whether combining two immunotherapy drugs (ipilimumab and nivolumab) with a procedure called immunoembolization can help people whose uveal melanoma has spread to the liver. The drugs help the immune system attack cancer cells, while immunoembolization cut…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
-
Can radiation reignite cancer control after immunotherapy fails?
Disease control CompletedThis phase II trial tests whether radiation therapy can help control cancer that has spread or grown after immunotherapy. About 230 patients with metastatic or lymphoid cancers will receive targeted radiation to see if it stabilizes the disease or shrinks tumors. The study also m…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
-
Double-Drug attack on tough lung cancer mutation
Disease control CompletedThis study tests whether combining two targeted drugs, avutometinib and adagrasib, can shrink tumors in people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. Participants must have already tried a KRAS G12C inhibitor and seen their c…
Phase 1/2 • Sponsor: Verastem, Inc. • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
-
New pill shows promise in shrinking Hard-to-Treat breast tumors
Disease control CompletedThis study tested a new oral drug called BGB-43395 in 33 Chinese patients with advanced or metastatic HR+/HER2- breast cancer and other solid tumors. The drug blocks a protein (CDK4) that helps cancer cells grow. The goal was to find a safe dose and see if it can shrink tumors wh…
Phase 1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
-
New shot form of cancer drug tested in 142 patients
Disease control CompletedThis study tested a new under-the-skin shot version of the cancer drug pembrolizumab (Keytruda) in 142 people with advanced solid tumors. The goal was to see how well the body absorbs the drug compared to the standard IV infusion. Researchers also checked for side effects and how…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
-
New antibody combo takes on advanced cancers in first human trial
Disease control CompletedThis early-stage trial tested an experimental drug called LVGN6051, which activates immune cells by targeting CD137, both alone and combined with the approved immunotherapy Keytruda. The study involved 105 adults with advanced or metastatic cancers that had spread. The main goal …
Phase 1 • Sponsor: Lyvgen Biopharma Holdings Limited • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
-
New radioactive compound shows promise in targeting Hard-to-Treat cancers
Disease control CompletedThis early-phase study tested a new radioactive drug called 177Lu-CTR-FAPI in 12 people with advanced solid tumors (breast cancer, sarcoma, or thyroid cancer) that had spread and no longer responded to standard treatments. The main goals were to see if the drug is safe and how it…
Early phase 1 • Sponsor: Lanzhou University Second Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
-
Radiation before brain surgery may stop cancer's return
Disease control CompletedThis study tested giving focused radiation before surgery to people with cancer that spread to the brain. The goal was to see if this approach is safe and might lower the chance of the tumor coming back. 26 adults with brain metastases took part. The treatment aims to control the…
Early phase 1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
-
New drug shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new drug called MRG004A in 39 adults with advanced or metastatic solid tumors that have a specific marker called tissue factor. The goal was to find the safest dose and see if the drug can shrink tumors. Researchers monitored side effects and how well the drug…
Phase 1/2 • Sponsor: Lepu Biopharma Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
-
New drug duo aims to reboot immune attack on Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested a new drug called M6223, which blocks a protein called TIGIT that can turn off immune cells. M6223 was given alone or together with another drug, bintrafusp alfa, to 58 people with advanced solid tumors that had stopped responding to standard treatme…
Phase 1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
-
One-Time radiation blast shows promise for containing limited metastatic cancer
Disease control CompletedThis study tested whether a single, high dose of targeted radiation can control cancer that has spread to just a few spots (1-5 tumors). 150 adults with limited metastatic cancer received this treatment to see if it could delay further spread and improve survival. The goal is to …
Sponsor: Fundacao Champalimaud • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
-
Experimental drug combo targets Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested a new drug called AZD8186 combined with the chemotherapy docetaxel in 23 patients with advanced solid tumors that have PTEN or PIK3CB gene mutations. The main goal was to find the safest dose and understand side effects. The study is complete, but re…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
-
New combo therapy shows promise for Tough-to-Treat colon cancer
Disease control CompletedThis early-phase study tested a combination of two drugs, cabozantinib and TAS-102, in 15 people with advanced colorectal cancer that had spread and stopped responding to standard treatments. The main goal was to find the safest dose and identify side effects. The study is comple…
Phase 1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested a combination of three drugs—vemurafenib, cetuximab, and irinotecan—in 47 people with advanced solid tumors that have a specific BRAF V600 mutation and could not be removed by surgery or had spread. The main goal was to find the safest dose and under…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
Virus injected into tumors shows promise in early breast cancer safety trial
Disease control CompletedThis early-stage trial tested a modified vaccinia virus (VV-GMCSF-Lact) injected directly into tumors of 34 women with recurrent or metastatic breast cancer that no longer responded to standard treatments. The main goal was to check safety and find the highest safe dose. Research…
Phase 1 • Sponsor: "Oncostar" LLC • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
New hope for cancer patients when immunotherapy fails?
Disease control CompletedThis early-stage trial tested an experimental drug called CTX-471, given alone or with the approved drug Keytruda, in 100 adults with advanced cancers like lung cancer, melanoma, and head and neck cancer. The goal was to see if the combination is safe and tolerable for patients w…
Phase 1 • Sponsor: Compass Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
-
Tailored chemo doses may help seniors fight pancreatic cancer while staying independent
Disease control CompletedThis study tested a chemotherapy cocktail called FOLFIRINOX in 72 patients aged 70 or older with metastatic pancreatic cancer. The doses were adjusted based on each person's genetics to reduce side effects while still fighting the tumor. The goal was to see if this approach could…
Phase 2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
-
Drug shows promise for kidney cancer brain metastases in early trial
Disease control CompletedThis phase 2 trial tested the drug sunitinib in 21 patients with kidney cancer that had spread to the brain. The goal was to see if the drug could shrink brain tumors by blocking blood flow and cell growth. Researchers measured how many patients had a response after two treatment…
Phase 2 • Sponsor: Institut Claudius Regaud • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
-
New drug combo shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new drug called TAK-676, alone and with pembrolizumab, in 248 adults with advanced solid tumors that had no standard treatment options. The main goal was to check safety and find the highest dose that causes few side effects. The study also looked at how well …
Phase 1/2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
-
Diabetes drug plus chemo shows promise in early cancer trial
Disease control CompletedThis early-phase trial tested the safety of combining pioglitazone (a diabetes drug) with carboplatin (a chemotherapy) in 14 people with advanced solid tumors that could not be cured with standard treatments. The goal was to find the best dose and see if the combination is safe. …
Phase 1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
-
Immune cell therapy shows promise in early trial for advanced cancers
Disease control CompletedThis early-phase study tested a new immune cell therapy called PD-L1 t-haNK in 16 adults with advanced solid cancers that had spread or could not be removed by surgery. The main goals were to check safety, find the best dose, and see if the treatment could shrink tumors. The ther…
Phase 1 • Sponsor: ImmunityBio, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
-
Experimental drug BAT8010 tested in patients with advanced cancers
Disease control CompletedThis early-phase trial tested an experimental drug called BAT8010 in 23 people with advanced or metastatic solid tumors who had no other standard treatment options. The main goals were to check safety, find the best dose, and see if the drug shows any sign of shrinking tumors. Pa…
Phase 1 • Sponsor: Bio-Thera Solutions • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
-
New drug duo shows promise for hard-to-treat cancers
Disease control CompletedThis early-phase trial tested a new drug called ALRN-6924 combined with the chemotherapy paclitaxel in 28 adults with advanced solid tumors that had spread or couldn't be removed by surgery, including a type of breast cancer. The main goal was to find the safest dose and check fo…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
-
New hope for liver cancer: triple therapy shows promise
Disease control CompletedThis study tests whether adding a third drug, ipilimumab, to the standard two-drug combination (atezolizumab and bevacizumab) improves survival and tumor shrinkage in people with advanced liver cancer. About 229 patients will receive either the standard two drugs or all three. Th…
Phase 2/3 • Sponsor: Federation Francophone de Cancerologie Digestive • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
-
New drug targets rare gene mutations in advanced cancers
Disease control CompletedThis phase II trial tested the drug infigratinib in 17 adults with advanced or metastatic solid tumors that have specific FGFR gene mutations. The drug works by blocking overactive FGFR proteins that help cancer grow. The study measured how many patients' tumors shrank or stabili…
Phase 2 • Sponsor: Sameek Roychowdhury • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
-
Cialis and keytruda together against head and neck cancer: small trial shows promise?
Disease control CompletedThis completed phase II study tested a combination of two drugs—tadalafil (Cialis) and pembrolizumab (Keytruda)—in 7 adults with advanced head and neck cancer that had spread or come back. The goal was to see if the combination was safe and could help control the disease. Because…
Phase 2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
-
New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new immunotherapy drug, ezabenlimab, combined with other cancer medicines in 211 adults with advanced solid tumors that had spread. The goal was to see if the tumors shrank or disappeared. Participants received different drug combinations, and doctors monitore…
Phase 2 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
-
New cancer pill shows promise in early trial
Disease control CompletedThis early-phase trial tested a new oral drug called ART4215 in 93 people with advanced or metastatic solid tumors, including breast cancer. The main goals were to find a safe dose and check for side effects when given alone or with other cancer drugs (talazoparib or niraparib). …
Phase 1 • Sponsor: Artios Pharma Ltd • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
-
Chemo-Immuno cocktail shows promise in early cancer trial
Disease control CompletedThis early-phase trial tested whether adding two chemotherapy drugs (6-mercaptopurine and 6-thioguanine) to an immunotherapy drug (Atezolizumab) could help treat advanced solid tumors that have stopped responding to standard treatments. The study enrolled 18 adults with metastati…
Phase 1/2 • Sponsor: Kristoffer Rohrberg • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
-
New cancer drug MRX-2843 enters first human trial
Disease control CompletedThis early-stage trial tested a new drug called MRX-2843 in 42 adults with advanced solid tumors that had spread or come back after other treatments. The main goal was to check safety and find the right dose. Researchers monitored side effects and how the drug moved through the b…
Phase 1 • Sponsor: Meryx, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
-
Experimental antibody combo tackles Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested an experimental drug called ADG116, which helps the immune system attack cancer cells. The study included 72 adults with advanced solid tumors that had stopped responding to standard treatments. Some participants received ADG116 alone, while others g…
Phase 1 • Sponsor: Adagene Inc • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
-
New cancer drug WTX-330 shows promise in early human trial
Disease control CompletedThis early-phase study tested a new drug called WTX-330 in 25 adults with advanced solid tumors or lymphoma that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the drug could shrink tumors. The study is now comp…
Phase 1 • Sponsor: Werewolf Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
-
New immune booster FL115 tested in patients with advanced cancers
Disease control CompletedThis early-phase trial tested a new drug called FL115 in 18 adults with advanced solid tumors that had stopped responding to standard treatments. FL115 is designed to strengthen the body's immune cells to fight cancer. The main goal was to check safety and find the right dose, wh…
Phase 1 • Sponsor: Suzhou Forlong Biotechnology Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
-
New pill shows promise in early trial for tough cancers
Disease control CompletedThis early-phase study tested an experimental oral drug called Q702 in 51 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects, while also looking at whether the drug could shrink …
Phase 1 • Sponsor: Qurient Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
-
New cancer drug shows promise in early trial
Disease control CompletedThis phase 1 study tested an experimental drug called LY3039478 in 247 people with advanced or metastatic cancer, including lymphoma. The main goal was to find a safe dose and see how the drug affects the body. Researchers also looked for signs that the drug might shrink tumors.
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
-
New radioactive compound shows promise in first human tests for advanced cancer
Disease control CompletedThis early-phase study tested a new radioactive drug called [177Lu]Lu-TEFAPI-06 in 5 people with advanced solid tumors that had spread and were no longer responding to standard treatments. The main goal was to check safety and see how the drug moves through the body. Researchers …
Early phase 1 • Sponsor: Lanzhou University Second Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
-
Immune cocktail shows promise in early trial for stubborn cancers
Disease control CompletedThis early-phase study tested a new mix of three drugs—IL-15, nivolumab, and ipilimumab—in 31 adults with cancers that no longer respond to standard treatments. The goal was to find the safest dose and see if the combination could help the immune system attack tumors. Participant…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
-
Experimental virus therapy takes on advanced tumors in early trial
Disease control CompletedThis early-phase study tested a new treatment called NG-350A, a virus designed to target tumors and boost immune activity, combined with the immunotherapy drug pembrolizumab. Fourteen people with advanced epithelial cancers that had stopped responding to standard treatments recei…
Phase 1 • Sponsor: Akamis Bio • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
-
New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new drug, TAK-981, combined with the immunotherapy pembrolizumab in 161 adults with advanced or metastatic solid tumors that could not be cured. The main goals were to check safety and see if the combination could shrink tumors. Participants received treatment…
Phase 1/2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
-
Lung cancer drug combo shows promise in early trial
Disease control CompletedThis early-phase study tested adding the drug pirfenidone to standard chemotherapy for people with advanced non-small cell lung cancer. The main goals were to find a safe dose and see if the combination could shrink tumors. 48 participants were enrolled, and the study is now comp…
Phase 1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
-
New drug duo shows early promise against advanced cancers
Disease control CompletedThis early-phase study tested a combination of two experimental drugs (AK127 and AK104) in 67 people with advanced or metastatic solid tumours that had stopped responding to standard treatments. The main goals were to check safety and find the right dose, while also looking for s…
Early phase 1 • Sponsor: Akesobio Australia Pty Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
-
New combo therapy aims to supercharge immune attack on tough cancers
Disease control CompletedThis study tested a combination of three immunotherapy drugs (ipilimumab, nivolumab, and BMS-986156) with or without precise radiation therapy in 51 people with advanced solid cancers that had spread to the liver or lungs. The goal was to find the safest dose of BMS-986156 and se…
Phase 1/2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
-
New drug cocktails tested for advanced cancers: hope or hype?
Disease control CompletedThis early-phase trial tested several combinations of cancer drugs, including niraparib, TSR-042, bevacizumab, and various chemotherapies, in 60 patients with advanced or metastatic cancer. The main goal was to find safe doses for future studies. The trial has been completed, but…
Phase 1 • Sponsor: Tesaro, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
-
Bacteria cocktail aims to boost cancer immunotherapy
Disease control CompletedThis study tested a combination of an oral bacterial product (VE800) and the immunotherapy drug nivolumab in 56 people with advanced or metastatic cancers like melanoma, stomach, and colorectal cancer. The goal was to see if the bacteria could help the immune system fight tumors …
Phase 1/2 • Sponsor: Vedanta Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
-
New combo therapy shows promise in early cancer trial
Disease control CompletedThis early-phase study tested an experimental drug (MK-1454) injected directly into tumors, either alone or with pembrolizumab (Keytruda), in 156 people with advanced solid tumors or lymphomas. The main goals were to find the safest dose and check for side effects. The study also…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
-
New drug cocktail shows promise in Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested two drugs—sapanisertib and ziv-aflibercept—in 83 people with advanced solid tumors that had spread or could not be removed. The goal was to find the safest dose and check for side effects. Sapanisertib blocks enzymes that help cancer cells grow, whil…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
-
New drug targets Hard-to-Treat cancers with rare gene mutation
Disease control CompletedThis early-stage study tested a new drug called PRT3789, alone or with chemotherapy (docetaxel), in people with advanced solid tumors that have a specific change in the SMARCA4 gene. The main goals were to check safety, find the best dose, and see if the drug shrinks tumors. 135 …
Phase 1 • Sponsor: Prelude Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
New antibody combo shows promise for Hard-to-Treat cancers
Disease control CompletedThis early-phase study tested a new antibody called HMBD-002, given alone or with pembrolizumab, in 48 adults with advanced solid tumors (like lung or breast cancer) that had stopped responding to standard treatments. The main goals were to check safety, find the best dose, and s…
Phase 1 • Sponsor: Hummingbird Bioscience • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis early-stage trial tested a new drug called vibostolimab, either alone or combined with other cancer drugs, in 474 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the dr…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
New drug combo tested for Hard-to-Treat cancers
Disease control CompletedThis early-stage study tested a new drug called MK-4464, given alone or with another drug (pembrolizumab), in 64 people with advanced solid tumors that had not responded to standard treatments. The main goals were to check the safety of the drug and how the body processes it. Thi…
Phase 1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
New cocktail of immune drugs shows promise for tough prostate cancer
Disease control CompletedThis study tested different combinations of immunotherapy drugs in 59 adults with advanced prostate cancer that no longer responds to hormone therapy. The goal was to see if these combinations are safe and can help shrink tumors or lower PSA levels. Participants received up to fo…
Phase 1/2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
Radiation plus immunotherapy: a one-two punch against metastatic cancer?
Disease control CompletedThis phase 2 trial tested whether adding stereotactic body radiation therapy (SBRT) to standard checkpoint immunotherapy improves tumor response in 106 people with advanced metastatic cancer. Participants received either immunotherapy alone or immunotherapy plus SBRT to one tumor…
Phase 2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
-
Cancer drug Trodelvy's Long-Term safety checked in small study
Disease control CompletedThis study looked at the long-term safety of the drug sacituzumab govitecan (Trodelvy) in 25 people with metastatic solid tumors who were already benefiting from the treatment. Participants continued to receive the drug intravenously, and researchers tracked any side effects or l…
Phase 4 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
-
Experimental immune therapy takes on stage IV cancers
Disease control CompletedThis early-stage trial tested a combination of immune cells in 9 people with stage IV solid tumors that had stopped responding to standard treatments. The main goal was to see if the therapy is safe and to check for any signs that it might control the disease. The study is now co…
Phase 1 • Sponsor: Seoul Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
-
New drug shows promise for tough head and neck cancers
Disease control CompletedThis study tested an experimental drug called ozuriftamab vedotin in 42 people with head and neck cancer that returned or spread. The goal was to see if the drug could shrink tumors and to check for side effects. Participants received the drug alone or with other treatments, and …
Phase 2 • Sponsor: BioAtla, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
-
Promising combo tackles tough lung cancer
Disease control CompletedThis study tested a new two-drug combination (bemcentinib plus pembrolizumab) in 99 adults with advanced lung cancer that had already been treated. The goal was to see if the combination could shrink tumors or stop them from growing. Participants received both drugs by mouth or I…
Phase 2 • Sponsor: BerGenBio ASA • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
-
Triple-Drug cocktail shows promise in Hard-to-Treat cancers
Disease control CompletedThis early-phase study tested a combination of three drugs—selinexor, nivolumab, and ipilimumab—in 11 adults with advanced or metastatic solid tumors that had stopped responding to standard treatments. The main goal was to check the safety and tolerability of the combination, whi…
Phase 1 • Sponsor: National University Hospital, Singapore • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
-
First human trial of SUPLEXA cells targets Hard-to-Treat cancers
Disease control CompletedThis early-stage trial tested a new therapy called SUPLEXA in 46 adults with advanced solid tumors or blood cancers that had spread. SUPLEXA is made from a patient's own immune cells, which are processed in a lab to become more active against cancer. The main goal was to check sa…
Phase 1 • Sponsor: Alloplex Biotherapeutics Inc • Aim: Disease control
Last updated Jun 26, 2026 18:11 UTC
-
New radiation approach targets dozens of tumors at once
Disease control CompletedThis study tested a new radiation technique called SABR in 13 adults with cancer that had spread to more than 10 spots in the body. The goal was to see if giving high-dose, precise radiation to all cancer sites is safe. Researchers looked for side effects and quality of life chan…
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated Jun 26, 2026 15:26 UTC
-
New cancer drug EVT801 tested in humans for first time
Disease control CompletedThis early-stage trial tested an experimental drug called EVT801 in 32 adults with advanced solid tumours that had stopped responding to standard treatments. The main goal was to check the drug's safety and find the best dose to use in future studies. Participants took EVT801 cap…
Phase 1 • Sponsor: Kazia Therapeutics Limited • Aim: Disease control
Last updated Jun 26, 2026 13:12 UTC
-
Blood test may cut cancer diagnosis time
Diagnosis CompletedThis study looked at whether using a liquid biopsy (a blood test that detects cancer DNA) early in the diagnostic process could help doctors diagnose and recommend treatment faster for people with advanced lung or gastrointestinal cancer. 463 participants were enrolled across mul…
Sponsor: Hoffmann-La Roche • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
-
New program aims to bridge racial gaps in end-of-life care
Symptom relief CompletedThis study tested a program called PRISM, which teaches skills like stress management and goal setting, to see if it helps racial minority patients with serious illnesses feel more resilient and communicate better with their healthcare providers. The study enrolled 28 seriously i…
Phase 1/2 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
-
Home workouts help cancer patients feel better during pandemic
Symptom relief CompletedThis study tested whether an online exercise and education program could help cancer patients and survivors feel better during the COVID-19 pandemic. Thirty adults with metastatic breast or gynecological cancer, or breast cancer survivors, took part. The program aimed to reduce f…
Sponsor: University of Malaga • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
-
Cancer pain study questions need for extra paracetamol pills
Symptom relief CompletedThis study looked at whether cancer patients already taking strong opioids like morphine can stop taking paracetamol without their pain getting worse. 204 adults with metastatic cancer and stable pain on both medications were randomly assigned to continue paracetamol or switch to…
Phase 3 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
-
New therapy helps lung cancer patients navigate life while facing death
Symptom relief CompletedThis study tested a program called LiveWell, which teaches practical skills to help people with metastatic lung cancer manage stress, anxiety, and sadness. One participant completed the 8-session video-based training. The goal was to see if the program is usable and helpful for i…
Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
-
Can a short therapy ease depression in advanced cancer?
Symptom relief CompletedThis study tested a short talking therapy called CALM for advanced cancer patients with depression. It involved 90 people in Korea and aimed to see if the therapy was practical and helpful. The therapy focuses on managing symptoms, relationships, and finding meaning.
Sponsor: Kyungpook National University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
-
Remote nutrition support boosts quality of life for advanced cancer patients
Symptom relief CompletedThis study tested whether a team of nutrition experts working remotely with doctors could improve the health and well-being of 158 people with stage IV cancer undergoing chemotherapy. The goal was to prevent weight loss, muscle loss, and poor nutrition, which are common but often…
Sponsor: Xingchen Peng • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
-
Magic mushroom compound tested to calm cancer anxiety
Symptom relief CompletedThis study tested whether psilocybin, a substance from certain mushrooms, given with therapy could safely reduce anxiety and depression in 55 people with metastatic cancer. Participants received counseling and a pharmaceutical-grade psilocybin dose. The trial focused on safety an…
Phase 1/2 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
-
Magic mushrooms again? study tests second retreat for cancer anxiety
Symptom relief CompletedThis phase 1 trial tested whether a second psilocybin-assisted group therapy retreat is safe and helpful for anxiety in 15 patients with metastatic cancer who had only a partial response to their first retreat. Psilocybin, the active ingredient in magic mushrooms, is given in a g…
Phase 1 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
-
Talking therapy shows promise for brain cancer distress
Symptom relief CompletedThis study tested a therapy called Managing Cancer and Living Meaningfully (CALM) to see if it helps people with brain cancer feel less distressed. 60 adults with brain tumors or brain metastases who had high depression or death anxiety took part. The study measured how many peop…
Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
-
Simple breathing drills may ease suffering for End-Stage cancer patients
Symptom relief CompletedThis study tested whether supervised breathing exercises could reduce pain, shortness of breath, and improve daily function in 58 terminal-stage cancer patients receiving palliative care. One group did diaphragmatic and pursed-lip breathing with a physiotherapist, while the other…
Sponsor: Atlas University • Aim: Symptom relief
Last updated Jun 26, 2026 15:38 UTC
-
Can a simple blood test guide cancer treatment? new study investigates.
Knowledge-focused CompletedThis study looks at whether analyzing the genes of a tumor (from a tissue sample or a blood test) can help doctors pick a more effective treatment for people with advanced solid cancers that have stopped responding to standard therapies. About 235 participants will have their tum…
Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
-
Can ultrasound predict cancer drug response earlier?
Knowledge-focused CompletedThis trial is testing whether contrast-enhanced ultrasound (CEUS) can reliably measure tumor blood flow in people with metastatic cancers like GIST, breast, kidney, colon, rectal, or melanoma. Participants will have two ultrasound scans before starting anti-angiogenic treatment, …
Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
-
Tissue analysis may guide personalized cancer therapy
Knowledge-focused CompletedThis study tests whether analyzing a patient's tumor alongside a sample of their normal tissue can help doctors select a more effective treatment for advanced cancer. The approach aims to provide a personalized therapy choice for every participant, even those without known geneti…
Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
-
Scientists track tumor evolution under immune attack in tiny study
Knowledge-focused CompletedThis study looks at how tumors evolve when treated with immune checkpoint inhibitors, a type of immunotherapy. Researchers will take blood samples and tumor biopsies from 14 people with advanced head and neck cancer or melanoma to track genetic changes. The goal is to understand …
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
-
Grip strength may predict cancer patient survival
Knowledge-focused CompletedThis completed study looked at 130 hospitalized cancer patients to see if hand grip strength could predict short-term outcomes like death within 30 days, ICU admission, or hospital readmission. Researchers measured grip strength within 24 hours of admission using a simple, non-in…
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
-
40,000 patients studied: does a simpler cancer drug dose work just as well?
Knowledge-focused CompletedThis completed study looked at 40,000 people with metastatic cancer who received the drug nivolumab. Researchers compared the old way of dosing (based on body weight) with a newer, simpler fixed dose. They used national health data to see if the fixed dose was just as good and mo…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
-
Study reveals why immunotherapy works differently in liver, lung, and brain tumors
Knowledge-focused CompletedThis study looked at medical records of 938 adults with solid tumors who received immunotherapy. Researchers compared how well the treatment worked when cancer had spread to different organs like the liver, brain, lung, or bone. The goal is to understand why some metastatic sites…
Sponsor: Wenlong Zhong, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
-
Can better talks help kids with cancer have a gentler end of life?
Knowledge-focused CompletedThis study tested a special communication program for doctors and parents of children with advanced cancer. The goal was to help families and doctors agree on treatment goals, especially for children nearing end of life. Researchers measured whether this improved the child's qual…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
-
New approach to CPR talks may help patients and families feel heard
Knowledge-focused CompletedThis study tested a new way for doctors to discuss CPR with older, seriously ill patients and their families. Instead of the usual conversation, doctors followed a step-by-step guide that focused on the patient's values and explained why CPR might not help. The goal was to see if…
Phase 2/3 • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
-
Blood tests and surveys may predict cancer treatment success
Knowledge-focused CompletedThis study followed 159 people with metastatic colorectal, pancreatic, biliary, or esophageal cancers who were starting a new line of therapy. Researchers collected blood samples (tumor markers and liquid biopsies) and patient-reported quality-of-life data to see if these could p…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
-
Iron deficiency in cancer: a hidden problem exposed
Knowledge-focused CompletedThis study looked at how common iron deficiency is in cancer patients starting chemotherapy. Researchers checked iron levels in 480 adults with solid tumors or lymphoma. The goal was to find out how many patients might benefit from iron injections, without using other drugs like …
Sponsor: Centre Antoine Lacassagne • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
-
New score could help guide Late-Stage breast cancer treatment decisions
Knowledge-focused CompletedThis study aims to develop and validate a scoring system to identify which patients with metastatic breast cancer are likely to live longer with third-line chemotherapy. Researchers will collect clinical, histological, and biological data from 267 women starting a third line of t…
Phase 4 • Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
-
Can a simple chat with your GP after cancer treatment keep you out of the hospital?
Knowledge-focused CompletedThis study tested whether a planned meeting between a hospitalized cancer patient, their family doctor, and a specialist could reduce unplanned hospital visits. 667 adults with metastatic solid tumors were randomly assigned to either the standard discharge process or this organiz…
Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
-
ER program helps patients talk about end-of-life wishes
Knowledge-focused CompletedThis study tested a program called ED GOAL that helps older adults with serious illnesses like heart failure or cancer discuss their end-of-life wishes with doctors and family, starting in the emergency department. Researchers enrolled 141 patients and measured whether the progra…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
-
New website helps cancer patients prepare for End-of-Life
Knowledge-focused CompletedThis study tested a website designed to help people with advanced cancer plan for end-of-life care, including medical wishes, legal documents, and financial tasks. About 100 patients took part to see if the tool reduced distress and improved planning. The goal was to learn whethe…
Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
-
Blood test may spot polyp cells that signal cancer risk
Knowledge-focused CompletedThis study tested whether a blood test can find tumor cells or substances released by intestinal polyps. Researchers compared blood samples from 120 people with and without polyps during a colonoscopy. The goal is to see if these markers could help predict or monitor cancer sprea…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
-
Planning ahead: study tests if care wishes are honored
Knowledge-focused CompletedThis study looked at whether a special planning tool, called a POST form, helps older adults (65+) get the medical care they prefer at the end of life. Researchers worked with 389 people, including those with dementia, to see if their treatment matched their wishes. The goal was …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
-
Gene-Guided cancer therapy put to the test in 742 patients
Knowledge-focused CompletedThis study tested whether choosing cancer drugs based on the genetic makeup of a patient's tumor works better than standard treatment. It included 742 adults with advanced solid tumors that had stopped responding to usual therapies. Patients were randomly assigned to receive eith…
Phase 2 • Sponsor: Institut Curie • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
-
Chicken eggs used to grow patient cancer cells in new automated system
Knowledge-focused CompletedThis study tested whether an automated system can grow cancer cells from patient samples (blood, fluid, or tumor tissue) inside chicken eggs. Researchers aimed to see if at least half of the samples would successfully grow. The goal is to create a better, cheaper way to study can…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
-
Mini-Tumor biobank could revolutionize cancer drug testing
Knowledge-focused CompletedThis completed study aimed to create a biobank of 'organoids'—tiny, 3D mini-tumors grown from liver cancer tissue. Researchers collected samples from 48 patients with colorectal cancer that spread to the liver or with primary liver cancer. The goal was to see if they could reliab…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
-
Can a simple booklet help cancer patients ask the right questions?
Knowledge-focused CompletedThis study tested whether giving cancer patients and their families a booklet of questions before a palliative care consultation helps them ask more questions or express more concerns. 121 adults with metastatic cancer and limited life expectancy took part. The booklet covered ei…
Sponsor: Institut Curie • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
-
Massive tumor study counts rare gene fusions
Knowledge-focused CompletedThis completed study examined tumor samples from 3820 people with advanced solid tumors to find how many have NTRK gene fusions. Researchers used genetic testing to identify these rare changes. The study did not test any treatment, but aims to guide future targeted therapy decisi…
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
-
New data on targeted breast cancer drugs from everyday practice
Knowledge-focused CompletedThis completed study looked at 312 patients with advanced breast cancer who received either trastuzumab deruxtecan or sacituzumab govitecan. Researchers collected real-world information on side effects and how long the cancer was kept under control. The goal was to see how these …
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:24 UTC
-
New study reveals key factors in 90-Day survival for advanced cancer patients after ER
Knowledge-focused CompletedThis completed study reviewed medical records of 1,250 advanced cancer patients who visited the emergency department. Researchers looked at factors like age, tumor type, and blood test results to see which patients were at higher risk of dying within 90 days. The goal is to help …
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:47 UTC
-
New program helps latino cancer patients voice their care wishes
Knowledge-focused CompletedThis study tested a program called PLAN to help Latino cancer patients plan for their future medical care. Twenty-seven patients with advanced cancer took part. The program aimed to improve their understanding and communication about advance care planning with doctors and family.…
Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:49 UTC