New drug PEP-010 shows promise in early trial for Hard-to-Treat cancers

NCT ID NCT04733027

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 25 times

Summary

This early-phase study tests a new drug called PEP-010, given alone or with chemotherapy (paclitaxel or gemcitabine), in people with metastatic solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose, and to see if the drug can shrink tumors in pancreatic and ovarian cancers. About 57 participants are enrolled across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CLCC F.Baclesse Caen

    Caen, France

  • Gustave Roussy

    Villejuif, France

  • Institut Curie

    Paris, 75005, France

  • Institut de Cancerologie de l'Ouest- ICO

    Saint-Herblain, 44805, France

Conditions

Explore the condition pages connected to this study.