Could an oral chemo pill improve breast cancer treatment?

NCT ID NCT07739485

First seen Jul 31, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This trial is testing an oral version of the chemotherapy drug paclitaxel, given after standard intravenous chemo, for people with triple-negative breast cancer. The study aims to find the safest and most effective dose of the oral paclitaxel. Participants will receive four cycles of epirubicin and cyclophosphamide, followed by four cycles of oral paclitaxel at one of three dose levels. The goal is to see how well this approach works in shrinking tumors before surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
paclitaxel oral solution
What this could lead to
If successful, this could offer a more convenient oral chemotherapy option for triple-negative breast cancer, potentially improving treatment adherence and outcomes.
What could go wrong
This is an early-phase dose-finding study with a small number of participants, so the optimal dose and effectiveness are not yet established. Side effects of paclitaxel, such as nerve damage and low blood counts, are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Affiliated Hospital of Guizhou Medical University

    RECRUITING

    Guiyang, Guizhou, China

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