New antibody combo shows promise for Hard-to-Treat cancers
NCT ID NCT05082610
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 28 times
Summary
This early-phase study tested a new drug called HMBD-002, alone or with another drug (pembrolizumab), in 48 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the best dose, and see if the drug helps shrink tumors. This is not a cure, but a step toward better control of advanced cancers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Smilow Cancer Hospital - Yale New Heaven Health
New Haven, Connecticut, 06511, United States
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Stanford Cancer Institute
Palo Alto, California, 94304, United States
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The City of Hope National Medical Center
Duarte, California, 91010, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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UTSW Medical Center
Dallas, Texas, 75390, United States
Conditions
Explore the condition pages connected to this study.