New drug combo targets Hard-to-Treat cancers in early trial

NCT ID NCT04670679

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new drug called ERAS-601, alone or with other cancer treatments, in adults with advanced solid tumors that have not responded to standard therapies. The main goals are to find safe doses and check for side effects. About 90 participants will take part across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chordoma colorectal neoplasm metastatic malignant neoplasm neoplasm Neoplasm Metastasis Noonan syndrome Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Comprehensive Cancer Centers of Nevada

    Henderson, Nevada, 89014, United States

  • Linear Clinical Research

    Perth, Western Australia, Australia

  • Mary Crowley Cancer Research

    Dallas, Texas, 75251, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02215, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, Australia

  • Sarah Cannon Research Institute (Florida Cancer Specialists)

    Sarasota, Florida, 34232, United States

  • Sarah Cannon Research Institute (Tennessee Oncology)

    Nashville, Tennessee, 37203, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Washington University

    St Louis, Missouri, 63110, United States