Can ultrasound predict cancer drug response earlier?

NCT ID NCT02666690

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This trial is testing whether contrast-enhanced ultrasound (CEUS) can reliably measure tumor blood flow in people with metastatic cancers like GIST, breast, kidney, colon, rectal, or melanoma. Participants will have two ultrasound scans before starting anti-angiogenic treatment, and again at day 15 and day 30. The goal is to see if the measurements are consistent enough to use CEUS as an early indicator of whether these drugs are working.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Contrast-enhanced ultrasound (CEUS)
What this could lead to
If the measurements are consistent, CEUS could become a reliable early test for whether anti-angiogenic drugs are working, helping doctors adjust treatment sooner.
What could go wrong
This is a small, early-stage variability study, not a treatment test. The results may not translate into routine clinical use, and the technique's reliability could vary across different tumor types.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gustave Roussy Cancer Campus Grand Paris

    Villejuif, Val de Marne, 94805, France

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