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Blood test may cut cancer diagnosis time

NCT ID NCT05846594

Completed Diagnosis Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether using a liquid biopsy (a blood test that detects cancer DNA) early in the diagnostic process could help doctors diagnose and recommend treatment faster for people with advanced lung or gastrointestinal cancer. 463 participants were enrolled across multiple countries. The study compared the time to diagnosis and treatment recommendation between those who had the liquid biopsy alongside standard care versus standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
FoundationOne® Liquid CDx Assay (a blood test that looks for cancer DNA)
What this could lead to
If successful, this could show that liquid biopsy helps doctors diagnose and recommend treatment for advanced cancer faster than traditional tissue biopsy alone.
What could go wrong
This is an observational study, not a treatment trial. It measures timing, not whether patients live longer or feel better. Results may not apply to all cancer types or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

digestive system cancer digestive system neoplasm lung cancer lung carcinoma lung neoplasm metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC GASTROINTESTINAL CANCER METASTATIC LUNG CANCER

Contacts and locations

Locations

  • Asklepios Klinik Gauting

    München-Gauting, 82131, Germany

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, Veneto, 37126, Italy

  • Azienda Ospedaliero-Universitaria Dipartimento Interaziendale Di Oncologia

    Udine, Friuli Venezia Giulia, 33100, Italy

  • CHU Strasbourg - Nouvel Hopital Civil

    Strasbourg, 67091, France

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre Oscar Lambret

    Lille, 59000, France

  • Clinica Universidad de Navarra Madrid

    Madrid, 28027, Spain

  • Gustave Roussy

    Villejuif, 94800, France

  • Hopital Marie Lannelongue

    Le Plessis-Robinson, 92350, France

  • Hospital Universitario Reina Sofia

    Córdoba, Cordoba, 14004, Spain

  • Hospital Universitario Son Espases

    Palma de Mallorca, Balearic Islands, 07014, Spain

  • Institut Sainte Catherine

    Avignon, 84918, France

  • Klinikum Stuttgart - Katharinenhospital

    Stuttgart, 70174, Germany

  • Klinikum der LMU München, Campus Großhadern, Krebszentrum München

    München, 81377, Germany

  • Med. Hochschule Hannover

    Hanover, 30625, Germany

  • Università degli Studi della Campania Luigi Vanvitelli

    Naples, Campania, 80131, Italy

  • Universität Mannheim

    Mannheim, 68167, Germany

  • Universitätsklinikum Hamburg-Eppendorf Onkologisches Zentrum Medizinische Klinik II

    Hamburg, 20246, Germany

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