New drug duo tested against advanced cancers

NCT ID NCT05021120

First seen Jan 06, 2026 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This early-phase study tested a new combination of two drugs, AK127 and AK104, in 67 people with advanced or metastatic solid tumours that had stopped responding to other treatments. The main goal was to check safety and find the right dose, while also looking at whether the tumours shrank. The study is now complete.

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Contacts and locations

Locations

  • Ashford Cancer Centre Research

    Adelaide, Australia

  • Austin Health

    Melbourne, Australia

  • Monash Health

    Melbourne, Australia

  • Southside Cancer Care Centre

    Sydney, Australia

  • The Kinghorn Cancer Centre, St Vincents Hospital Sydney

    Sydney, Australia

Conditions

Explore the condition pages connected to this study.