New drug combo shows promise in early cancer trial

NCT ID NCT05479812

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug called WTX-124, given alone or with another drug (pembrolizumab), in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. About 150 adults with certain types of cancer will take part. This is not a cure, but a step toward better disease control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma Melanoma, Cutaneous Malignant metastatic malignant neoplasm neoplasm Neoplasm Metastasis non-small cell lung carcinoma renal cell carcinoma skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • HonorHealth

    Scottsdale, Arizona, 85258, United States

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Minnesota Oncology Hematology, P.A.

    Maple Grove, Minnesota, 55369, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • NEXT Oncology

    Houston, Texas, 77054, United States

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Providence Cancer Institute Franz Clinic

    Portland, Oregon, 97213, United States

  • Roswell Park Comprehensive Cancer Care

    Buffalo, New York, 14203, United States

  • Texas Oncology - Austin Midtown

    Austin, Texas, 78705-1165, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-8852, United States

  • Westchester Medical Center

    Hawthorne, New York, 10532, United States