Triple-Drug cocktail shows promise in Hard-to-Treat cancers

NCT ID NCT04850755

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a combination of three drugs—selinexor, nivolumab, and ipilimumab—in 11 adults with advanced or metastatic solid tumors that had stopped responding to standard treatments. The main goal was to check the safety and tolerability of the combination, while also measuring how well it controlled tumor growth. Results help guide future research on this multi-drug approach.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National University Hospital, Singapore

    Singapore, Singapore