Experimental triple therapy shows promise for stubborn tumors

NCT ID NCT03388632

First seen Jan 04, 2026 · Last updated May 11, 2026 · Updated 21 times

Summary

This early-phase study tested a combination of three drugs—interleukin-15 (IL-15), nivolumab, and ipilimumab—in 31 adults with cancers that no longer respond to standard treatments. The goal was to find the safest dose and see if the drugs could help the immune system attack tumors. Participants received the drugs in cycles, with close monitoring for side effects. The study focused on safety and dosing, not on curing the cancer.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.