Immune cocktail shows promise in early trial for stubborn cancers

NCT ID NCT03388632

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a new mix of three drugs—IL-15, nivolumab, and ipilimumab—in 31 adults with cancers that no longer respond to standard treatments. The goal was to find the safest dose and see if the combination could help the immune system attack tumors. Participants received the drugs in cycles and were monitored closely for side effects and tumor response.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm refractory malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States