Can your own immune cells fight advanced cancer?
NCT ID NCT07743723
First seen Aug 04, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This trial is testing an experimental therapy called IOV-5001, which uses a patient's own immune cells (tumor-infiltrating lymphocytes) to attack cancer. The study involves adults with advanced solid tumors, including non-small cell lung cancer, triple-negative breast cancer, colorectal cancer, and head and neck cancer, that have not responded to prior treatments. Participants receive two infusions of their personalized cell therapy in a hospital setting. The goal is to see if this approach is safe and can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- IOV-5001, a personalized cell therapy made from a patient's own tumor-infiltrating lymphocytes (TILs)
- What this could lead to
- If successful, this could offer a new treatment option for people with advanced solid tumors that have not responded to other therapies, potentially leading to durable remissions.
- What could go wrong
- This is an early-stage trial, so the therapy may not work for everyone or may cause severe side effects. The treatment involves a complex process and requires hospitalization.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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