Cancer's hiding spots matter: study reveals organs react differently to immunotherapy

NCT ID NCT07631611

First seen Jun 16, 2026 · Last updated Jun 19, 2026 · Updated 2 times

Summary

This study looked at medical records of 938 adults with solid tumors to see how cancers that spread to different organs—like the liver, brain, lung, or bone—respond to immunotherapy. The goal is to understand why some metastatic sites respond better than others and to help doctors personalize treatment. Researchers also analyzed molecular data to explore the biological reasons behind these differences.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

immune checkpoint inhibitors (PD-1, PD-L1, CTLA-4 inhibitors)

What this could lead to

If successful, this could help doctors choose better immunotherapy treatments based on where a patient's cancer has spread.

What could go wrong

This is a retrospective study that looks back at medical records, so it cannot prove cause and effect. Results may not apply to all patients or treatments.

Conditions

The condition(s) this trial relates to.

brain cancer metastatic carcinoma in the bone metastatic malignant neoplasm metastatic malignant neoplasm in the brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.