Can an immune booster after lung cancer surgery keep the disease at bay?
NCT ID NCT07748325
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial asks whether giving sintilimab, an immune checkpoint inhibitor, after complete surgical removal of non-small cell lung cancer can improve outcomes for patients at high risk of recurrence. Participants who already received chemotherapy plus an immune checkpoint inhibitor before surgery are randomly assigned to either receive sintilimab for up to a year or to be observed without additional treatment. The main goal is to see if sintilimab improves the proportion of patients who remain cancer-free at 18 months after surgery, with secondary focus on overall survival and safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sintilimab, an immune checkpoint inhibitor, given intravenously every 4 weeks for up to 1 year after surgery.
- What this could lead to
- If effective, this could reduce the chance of lung cancer returning after surgery, potentially improving long-term survival for high-risk patients.
- What could go wrong
- This is a phase II trial with a modest size, so results may not be definitive. Sintilimab can cause immune-related side effects, and not all patients may benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADJUVANT THERAPY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Suining Central Hospital
RECRUITINGSuining, Sichuan, China
-
West China Hospital, Sichuan University
RECRUITINGChengdu, Sichuan, 610041, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new immunotherapy combo outsmart advanced lung cancer?
- Double attack on mutant KRAS: can two targeted drugs outsmart resistant cancers?
- Seeing the fight: new imaging tracer may reveal how immune cells attack lung cancer
- Could a bronchial wash detect lung cancer mutations faster?
- Can a targeted pill outsmart a tough lung cancer mutation?
- Can a PET scan reveal hidden heart harm from lung cancer treatment?