Sichuan University

This study tests a new drug called sunvozertinib combined with chemotherapy in people with advanced non-small cell lung cancer that has specific EGFR mutations. Participants must have already tried and failed an EGFR-targeted therapy. The goal is to see if the combination can shr…

This early-phase study is testing whether a combination of low-dose radiation to the whole brain, an immunotherapy drug (PD-1 inhibitor), and chemotherapy given directly into the spinal fluid can safely treat lung cancer that has spread to the lining of the brain and spinal cord.…

This study tests a new treatment for people with a specific type of advanced small cell lung cancer (SLFN-11 positive). The treatment combines low-dose radiation, chemotherapy, an immunotherapy drug (sugemalimab), and a targeted drug (olaparib). The goal is to see if this combina…

This early-stage trial tests a combination of low dose radiotherapy, focused radiation (SBRT), and the immunotherapy drug tislelizumab in people with large solid tumors that have not responded to standard treatments. The study aims to see if this approach is safe and tolerable. A…

This study looks at whether intensive nutritional support can help patients with advanced esophageal cancer who are receiving chemotherapy and immunotherapy before surgery. About 118 participants will be randomly assigned to either standard care or extra oral nutrition supplement…

This study tests whether adding a low dose of radiation to a combination of chemotherapy and an immunotherapy drug (adebrelimab) helps people with extensive-stage small cell lung cancer live longer. About 202 adults aged 18-75 who have not had prior treatment for this stage will …

This phase 2 trial is testing whether giving a combination of low-dose radiation, stereotactic body radiotherapy (SBRT), the immunotherapy drug tislelizumab, and standard chemotherapy before surgery can improve outcomes for people with stage II to III non-small cell lung cancer. …

This phase 2 trial tests whether adding low-dose radiation to standard immunotherapy (sintilimab) and chemotherapy can shrink tumors better than immunotherapy and chemo alone in people with advanced squamous cell lung cancer. About 114 participants will be randomly assigned to on…

This study tests whether injecting a cancer-killing virus directly into tumors, combined with standard chemotherapy and an immunotherapy drug, can shrink advanced esophageal cancer enough to allow surgery. About 40 adults with unresectable locally advanced esophageal squamous cel…