New cancer drug MRX-2843 enters first human trial

NCT ID NCT03510104

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested a new drug called MRX-2843 in 42 adults with advanced solid tumors that had spread or come back after other treatments. The main goal was to check safety and find the right dose. Researchers monitored side effects and how the drug moved through the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRX-2843

What this could lead to

If it works, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.

What could go wrong

This is a very early, small Phase 1 trial focused on safety and dosing, not effectiveness. Many experimental cancer drugs fail to show benefit in later stages.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer metastatic malignant neoplasm metastatic neoplasm neoplasm Neoplasm Metastasis Neoplastic Processes Pathologic Processes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27514, United States