New cancer drug EVT801 tested in humans for first time

NCT ID NCT05114668

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tested an experimental drug called EVT801 in 32 adults with advanced solid tumours that had stopped responding to standard treatments. The main goal was to check the drug's safety and find the best dose to use in future studies. Participants took EVT801 capsules by mouth daily.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EVT801 (an experimental drug taken orally as a capsule)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced solid tumours that have not responded to other therapies.

What could go wrong

This is a very early, small Phase 1 trial with only 32 participants. Its main goal is safety and dosing, not effectiveness. Many early-stage drugs do not go on to become approved treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm neoplasm Neoplasm Metastasis renal cell carcinoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Léon Bérard

    Lyon, 69373, France

  • Institut Universitaire du Cancer Toulouse - Oncopole

    Toulouse, 31059, France