40,000 patients studied: does a simpler cancer drug dose work just as well?

NCT ID NCT05380336

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 40,000 people with metastatic cancer who received the drug nivolumab. Researchers compared the old way of dosing (based on body weight) with a newer, simpler fixed dose. They used national health data to see if the fixed dose was just as good and more cost-effective over one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nivolumab

What this could lead to

If successful, this study could show that a simpler fixed-dose regimen is just as effective and more cost-efficient than weight-based dosing for metastatic cancer patients.

What could go wrong

This is an observational study using existing health data, not a controlled trial. Results may be influenced by differences between patient groups, and the one-year follow-up may not capture long-term outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

kidney cancer melanoma metastatic malignant neoplasm metastatic melanoma Neoplasm Metastasis non-small cell lung carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Nantes

    Nantes, 44093, France