Can a short therapy ease depression in advanced cancer?

NCT ID NCT07355153

Completed Symptom relief Sponsor: Kyungpook National University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a short talking therapy called CALM for advanced cancer patients with depression. It involved 90 people in Korea and aimed to see if the therapy was practical and helpful. The therapy focuses on managing symptoms, relationships, and finding meaning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Managing Cancer and Living Meaningfully (CALM) therapy
What this could lead to: If it works, this could offer a practical way to ease depression and existential distress in people with advanced cancer.
What could go wrong: This is a small, early feasibility study in one country, so results may not apply broadly. The therapy may not significantly improve depression in larger trials.

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Conditions

The condition(s) this trial relates to.

Behavioral Symptoms Depression depressive disorder metastatic malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION

Contacts and locations

Locations

Kyungpook National University Chilgok Hospital

Daegu, 41404, South Korea
Kyungpook National University Hospital

Daegu, 41944, South Korea

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