New drug combo targets Hard-to-Treat cancers
NCT ID NCT06460961
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests an experimental drug called MK-6837, given alone or with another drug (pembrolizumab), in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug shrinks tumors. About 168 adults with various metastatic cancers will take part.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atlantic Health System Morristown Medical Center ( Site 4001)
Morristown, New Jersey, 07960, United States
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Princess Margaret Cancer Centre ( Site 2001)
Toronto, Ontario, M5G 2M9, Canada
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Providence Portland Medical Center ( Site 4002)
Portland, Oregon, 97213, United States
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Sheba Medical Center-ONCOLOGY ( Site 3001)
Ramat Gan, 5265601, Israel
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South Texas Accelerated Research Therapeutics (START) ( Site 4003)
San Antonio, Texas, 78229, United States
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The Alfred Hospital ( Site 1001)
Melbourne, Victoria, 3004, Australia
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Westmead Hospital ( Site 1002)
Westmead, New South Wales, 2145, Australia