New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT03725436

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This early-stage trial tested a new drug called ALRN-6924 combined with the chemotherapy paclitaxel in 28 adults with advanced solid tumors that had spread or couldn't be removed by surgery, including a type of breast cancer. The main goal was to find the safest dose and check for side effects. Researchers also looked at whether the tumors shrank or disappeared after treatment.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.