TYPE 1 DIABETES

This pilot study tested the safety and effectiveness of an AI-powered advisor that helps adjust settings on an automated insulin pump system for very young children with type 1 diabetes. Thirty-three children aged 2 to 6 used the system at home for eight weeks. The goal was to se…

This study tested a special training program called ONBOARD, designed to help adults with type 1 diabetes who are new to continuous glucose monitors (CGMs). The goal was to teach people how to get the most benefit from the device, manage daily challenges, and get ready for future…

This study aimed to find out if a newer, more expensive type of insulin (glargine) works better than older, cheaper human insulin for young people with type 1 diabetes in low-resource settings. It involved 400 participants aged 7-25 and measured how well each insulin controlled b…

This study looked at how well automated insulin pumps, also called closed-loop systems, work for people with Type 1 diabetes in their daily lives. It followed 410 patients who were already using these devices to see how well they controlled their long-term blood sugar levels. The…

This study tested whether a mobile app that guides personalized strength training could help children and teenagers with type 1 diabetes. Researchers enrolled 62 participants to use the app for 24 weeks, aiming to see if it could safely reduce their daily insulin needs. The study…

This study aimed to see if a new, more concentrated version of insulin lispro (200 units/ml) works the same in the body as the standard version (100 units/ml). It involved 90 adults with type 1 diabetes who received a single dose of each insulin in a random order. Researchers use…

This study tested a new automated insulin delivery system (artificial pancreas) that can detect when someone with type 1 diabetes eats a meal but forgets to tell their insulin pump. The system then automatically gives the needed insulin. Researchers compared this new system again…

This study tested whether combining two immune-modifying treatments—abatacept (a weekly injection) and nasal insulin (a spray)—could help protect the pancreas's remaining insulin-producing cells in children and young adults recently diagnosed with type 1 diabetes. The goal was to…

This study tested whether the Omnipod 5 automated insulin delivery system helps people with type 1 diabetes better control their blood sugar compared to their usual insulin pumps. About 200 adults already using insulin pumps tried either the new Omnipod 5 system or continued with…

This small study tested if a faster-acting insulin (Lyumjev) works better in an automated insulin pump system for teenagers and young adults with type 1 diabetes. Researchers compared how well it kept blood sugar in a healthy range versus standard insulins (Humalog or Novolog). T…

This small, early-stage study tested the safety and side effects of a new oral treatment called R-5280 in teenagers recently diagnosed with Type 1 diabetes. For 12 weeks, participants took either the treatment or a placebo pill. Researchers checked for side effects and also measu…

This study looked back at medical records to compare two fast-acting insulins (Fiasp® and NovoRapid®) in children and teens with type 1 diabetes who use insulin pumps. Researchers wanted to see which insulin helped keep blood sugar in the target range more often and caused fewer …

This study looked at how well automated insulin delivery systems work for physically active adults with type 1 diabetes. Researchers observed 76 people for 6 weeks, comparing commercial systems with homemade 'DIY' versions, to see how they managed blood sugar levels before, durin…

This small pilot study tested whether a team-based approach could help adults with type 1 diabetes who are at high risk for a dangerous complication called diabetic ketoacidosis (DKA). Researchers had participants share their real-time glucose data with a chosen family member or …

This study tested two versions of an automated insulin delivery system, often called an artificial pancreas, in 15 adults with type 1 diabetes. Researchers wanted to see if a system that automatically gives both insulin and a hormone called glucagon works better at preventing low…

This study tested whether sending daily text message reminders could help teenagers with poorly controlled type 1 diabetes improve their blood sugar management. Researchers enrolled 92 adolescents and randomly assigned some to receive standard care plus text message support for 6…

This study tested whether specially trained community health workers could help young adults from underrepresented minority groups start and keep using diabetes technology like continuous glucose monitors and insulin pumps. For 9 months, 119 participants were randomly assigned to…

This study compared two diets for adults with type 1 diabetes and obesity. Researchers tested if eating all meals within a 6-8 hour window each day (time-restricted eating) works better for weight loss and blood sugar control than traditional daily calorie counting. The goal was …

This study tested if taking a dose of oral glucose *before* blood sugar drops too low (at a higher threshold) could help people with type 1 diabetes spend less time in dangerous hypoglycemia. It involved 30 adults with type 1 diabetes to see if this proactive approach works bette…

This study tested whether a program to help young adults with type 1 diabetes get more and more consistent sleep could improve their blood sugar control. Researchers compared a sleep coaching program to standard diabetes education in 39 participants. The goal was to see if better…

This study tested a one-year coaching program designed to help teens and young adults (ages 14-25) with type 1 diabetes. The program involved monthly sessions focused on reducing the stress of managing diabetes and improving blood sugar control. Researchers compared the coaching …

This study tested a peer support program for young adults (ages 17-25) with type 1 diabetes as they move from pediatric to adult healthcare. Trained mentors, who also have type 1 diabetes, provided guidance and shared their own experiences over 12 months. The main goal was to see…

This study tested whether regular check-in calls and visits from nurses could help teenagers with type 1 diabetes better accept their condition and improve their blood sugar control. 77 teens with higher-than-target blood sugar levels were randomly assigned to receive either thei…

This study tested a new insulin called THDB0206 against a standard insulin combination in Chinese adults with type 1 diabetes. Over 26 weeks, researchers measured how well it controlled blood sugar levels and monitored safety. The goal was to see if the new insulin could be a hel…

This study tested whether transplanting insulin-producing cells (islets) could help patients with type 1 diabetes who already had a kidney transplant. The goal was to help these patients become independent from insulin injections and better control their blood sugar. Researchers …

This study tested whether a weekly injection called semaglutide could help adults who have both type 1 diabetes and obesity. The 115 participants were already using an automated insulin pump system but still had difficulty managing their blood sugar. For 26 weeks, half received t…

This study tested if a new, faster-acting insulin works better in an automated 'artificial pancreas' system for people with type 1 diabetes. Twelve adults who already used the system tried the new insulin for 30 days and compared it to their usual insulin. The main goal was to se…

This small study tested if a diet low in carbohydrates could help children and teenagers with type 1 diabetes better control their blood sugar levels. Researchers compared this approach to the standard recommended diet over a short period. The goal was to see if eating fewer carb…

This study tested if using a newer, automated insulin pump system with stricter blood sugar targets could help adults with type 1 diabetes who have trouble managing their levels. Researchers enrolled 40 adults who were switching from insulin injections or older pump systems. The …

This study tested a new mobile app designed to help middle-aged adults with type 1 diabetes exercise more often and with more confidence. The app uses personal data like blood sugar levels, exercise, mood, and sleep to provide personalized encouragement and insights. Researchers …

This study tested a new, fully automated insulin delivery system for people with Type 1 diabetes. Fifteen adults stayed in a hotel for four nights to try the system with and without a special feature designed to handle meals. Researchers measured how well the system kept blood su…

This study tested whether stem cell injections could protect the body's insulin-producing cells in people recently diagnosed with type 1 diabetes. Researchers gave 63 participants either the stem cell treatment or a placebo to see if it could slow or stop the immune system's atta…

This study tested a new connected insulin pen system to see if it helps people with type 1 or type 2 diabetes remember to take their insulin doses on time. Researchers measured how often doses were missed and tracked blood sugar control in about 36 participants. The goal was to s…

This study tested if using the latest automated insulin delivery technology along with a low-carbohydrate diet could help restore the body's natural defense against dangerously low blood sugar (hypoglycemia) in people with type 1 diabetes. Twenty-four participants with long-term …

This study tested if adding a second drug, pramlintide, to an automated insulin delivery system could better control blood sugar after meals for people with type 1 diabetes. Thirty-three adults tried the system using insulin alone on one clinic day and insulin plus pramlintide on…

This study checked if a specific insulin pump and glucose monitor system is safe for very young children with type 1 diabetes to use at home. It involved 56 children between the ages of 2 and 6. Researchers monitored the children for about 130 days to see how well the system work…

This study tested whether group doctor visits could help underserved children aged 8-12 with poorly controlled type 1 diabetes. Over 12 months, small groups of children and their caregivers met quarterly with a medical team to learn about diabetes technology and management. The g…

This study tested whether a program using text message reminders and small rewards could help teenagers with type 1 diabetes take their mealtime insulin more consistently. Researchers enrolled 173 teens who were already using insulin pumps but struggling with their daily insulin …

This study tested whether an automated insulin delivery system could better control blood sugar in hospitalized adults with type 1 or type 2 diabetes compared to standard insulin injections. 130 participants were randomly assigned to use either the automated system or receive sta…

This study tested a new insulin patch pump system to see if it works as well as a standard insulin pump for controlling blood sugar. 161 adults with type 1 or type 2 diabetes were randomly assigned to use either the new patch pump or a standard pump for one week in a hospital set…

This study aimed to see if an automated insulin delivery system (an 'artificial pancreas') helps teenagers with type 1 diabetes better manage their blood sugar levels over two years, especially during puberty. It involved 42 adolescents, comparing those using the automated system…

This study tested if adding a 12-week home high-intensity interval training program to standard education could help adults with type 1 diabetes regain their ability to feel the early warning signs of dangerously low blood sugar (hypoglycemia). Forty-seven participants, who had l…

This study tested three different 3-month support programs to help adults with type 1 diabetes manage the emotional stress and worry that comes with daily disease management. About 300 participants were split into groups to try either a program focused on emotions, one focused on…

This study aimed to test a Turkish version of a questionnaire that measures nutrition knowledge in teenagers with type 1 diabetes. Researchers enrolled 150 adolescents and their parents to see if the questionnaire was reliable and valid. They also investigated whether higher nutr…

This study aimed to understand what happens in a child's body before type 1 diabetes develops. Researchers followed 512 babies born to parents with type 1 diabetes, who have a higher risk. They collected blood samples and health information over time to look for early immune syst…

This study looked at whether an online peer support group could help teenagers with Type 1 Diabetes. Ten teens aged 16-19 joined a private chat group for three months. Researchers observed how much they used the group and asked for their feedback to see if it was helpful and easy…

This study aimed to find a better way to predict dangerous low blood sugar (hypoglycemia) in people with Type 1 diabetes. Researchers tested 62 participants to see if measuring a hormone called glucagon after they ate a meal could act as a warning sign for future hypoglycemia. Th…

This study aimed to understand if the hormone oxytocin affects how the body of a person with type 1 diabetes responds to dangerously low blood sugar. Sixteen participants with type 1 diabetes received either oxytocin or a placebo during a controlled low-blood-sugar test. Research…

This study aimed to understand how daily stress, anxiety, and mood affect blood sugar control in teens and young adults with type 1 diabetes. Researchers tracked 47 participants aged 13-26 using smartphone surveys and continuous glucose monitors to see the connection between feel…

This study aimed to find out how common obstructive sleep apnea is in adults with type 1 diabetes who use insulin pumps. Researchers enrolled 825 participants to measure sleep apnea and see if it is connected to diabetes-related health problems like heart, kidney, or nerve issues…

This early research study explored whether the antidepressant fluoxetine (Prozac) could improve the body's automatic nervous system responses during exercise in people with Type 1 diabetes. The goal was to see if the medication could help prevent dangerous drops in blood sugar (h…

This study aimed to find simpler blood and urine tests to measure how many insulin-producing cells remain in people recently diagnosed with type 1 diabetes. Researchers followed 156 children and adults for 30 months, collecting samples to see if immune cell activity or other mark…

This study aimed to understand if a child's diagnosis of Type 1 Diabetes affects how well the family follows recommended vaccination schedules. Researchers observed 60 children with diabetes and their siblings to see if they received all their required and suggested shots. The go…

This study aimed to understand how common post-traumatic stress disorder (PTSD) is among adults with type 1 diabetes. Researchers surveyed 297 adults to see if their diabetes diagnosis or experiences with severe low blood sugar (hypoglycemia) were linked to PTSD symptoms. The goa…

This study aimed to find the best time to exercise to help control blood sugar after meals for women with type 1 diabetes, including those who are pregnant. Researchers compared the effects of a short walk before lunch versus after lunch in 20 women. The goal was to gather knowle…