Can a simple blood test track beta-cell loss in type 1 diabetes?

NCT ID NCT01747967

Completed Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether immune cell responses can serve as a simpler way to measure how many insulin-producing beta cells remain in people with type 1 diabetes. Researchers followed 156 participants over 30 months, using meal tests and blood/urine samples. The goal was to find better markers than the current cumbersome test, which could help monitor disease progression and future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to simpler blood or urine tests to track remaining beta-cell function in type 1 diabetes, aiding treatment monitoring.
What could go wrong: This is an observational study, not testing a treatment. The immune markers may not correlate well with beta-cell mass, limiting their usefulness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance type 1 diabetes mellitus type 1 diabetes mellitus 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 1 DIABETES

Contacts and locations

Locations

INSERM U1016 - DeAR Lab Avenir, Hôpital Cochin

Paris, 75014, France

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