TYPE 1 DIABETES

This study tests whether a special education plan using continuous ketone monitoring can lower the risk of diabetic ketoacidosis (DKA) in people with type 1 diabetes who also take SGLT2 inhibitors. About 75 adults with type 1 diabetes will be enrolled. The goal is to see if this …

This study tests whether a program that combines psychological support, diet changes, targeted therapy, and parent counseling can improve behavior and thinking in children with Type-1 diabetes who have hypoglycemia unawareness (not feeling low blood sugar). About 50 children aged…

This study tests a program that delivers fresh produce to the homes of pregnant women with type 1 or 2 diabetes who also struggle to get enough healthy food. Participants will also receive group education on diabetes, nutrition, and cooking, plus ongoing support for other needs. …

This pilot study at Stanford University will enroll 16 children and teens recently diagnosed with type 1 diabetes (within the past 2 weeks). The goal is to see if starting an automated insulin delivery (AID) system early helps them manage blood sugar more easily and stick with it…

This study tests whether a weekly medication called tirzepatide can help adults with type 1 diabetes use their insulin pump without counting carbohydrates at meals. About 105 participants in Canada and Switzerland will be randomly assigned to receive tirzepatide or continue stand…

This study looks at whether starting automated insulin delivery (AID) early in children aged 7-16 with new type 1 diabetes can improve blood sugar control, reduce stress for families, and lower the risk of future complications like eye or kidney disease. About 100 kids will be ra…

This study tests whether sorafenib, a drug currently used for cancer, can help people with newly diagnosed type 1 diabetes keep making some of their own insulin. Ten adults aged 18-60 will receive either sorafenib or a placebo for a short time. The goal is to see if the drug can …

This study tests a new medicine called IMC-S118AI in people with type 1 diabetes. The main goal is to see if it is safe and how the body processes it. Researchers will also check if it can help preserve the cells that make insulin. About 154 adults with a specific genetic type (H…

This study follows 40 adults with type 1 diabetes who previously used an automated insulin delivery system. Researchers want to see if the system's benefits, like better blood sugar control, last for several years. They will also check if long-term use leads to weight gain.

This study explores whether 8 weekly telehealth music therapy sessions can improve quality of life and reduce depression and anxiety in adults with autoimmune endocrine diseases (like Type 1 diabetes or Hashimoto's) and depression. Ten participants will have video sessions with a…

This study tests a new program called REDCHiP for parents of young children (up to age 8) with type 1 diabetes. The program aims to reduce parents' fear of hypoglycemia (low blood sugar) and diabetes-related distress. About 44 parents will be randomly assigned to either the progr…

This study looks at whether a special tool can help young adults (ages 18-30) with type 1 diabetes and their doctors work together to make care plans that fit daily life better. Researchers will compare usual doctor visits with visits using the 'Making Care Fit' tool. Participant…

This observational study will measure how often fatty liver and liver scarring occur in 100 adults with type 1 diabetes or LADA in Quebec. Participants will have a single visit for a non-invasive liver scan (FibroScan) and questionnaires. The goal is to find undiagnosed liver pro…

This study looks at how insulin affects muscle, blood, and the body in people with type 1 diabetes. Researchers will measure protein changes when insulin is low and blood sugar is high. About 70 adults with type 1 diabetes will take part. No treatment is tested; the goal is to le…

This study will follow 1300 women with type 1 diabetes who have had a pregnancy. Researchers want to see if a high risk of preeclampsia (a dangerous pregnancy condition) in the first trimester is linked to signs of heart disease and other health problems years later. Participants…

This study looks at how non-nutritive sweeteners (like those in diet drinks) affect the heart and blood vessels of young adults with type 1 diabetes. Twenty people aged 15-24 will drink a sports drink and have their blood vessel function measured. The goal is to understand if the…