New trial aims to match diabetes drugs to patients for better heart and kidney protection

NCT ID NCT07594145

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial will test two drugs, finerenone and sotagliflozin, in 57 people with type 1 diabetes who are at risk for heart and kidney problems. The goal is to see if matching the right drug to each person's specific diabetes subtype can improve early signs of heart and kidney health. The study will measure changes in urine protein and a heart stress marker over 26 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

finerenone and sotagliflozin

What this could lead to

If successful, this trial could show that matching specific diabetes subtypes to targeted drugs helps protect the heart and kidneys in people with type 1 diabetes.

What could go wrong

This is a small, early-phase trial (57 people) testing short-term effects. The drugs may not work as hoped, and side effects are possible. Results may not apply to everyone with type 1 diabetes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetic kidney disease heart failure type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact