New trial aims to match diabetes drugs to patients for better heart and kidney protection
NCT ID NCT07594145
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This phase 2 trial will test two drugs, finerenone and sotagliflozin, in 57 people with type 1 diabetes who are at risk for heart and kidney problems. The goal is to see if matching the right drug to each person's specific diabetes subtype can improve early signs of heart and kidney health. The study will measure changes in urine protein and a heart stress marker over 26 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- finerenone and sotagliflozin
- What this could lead to
- If successful, this trial could show that matching specific diabetes subtypes to targeted drugs helps protect the heart and kidneys in people with type 1 diabetes.
- What could go wrong
- This is a small, early-phase trial (57 people) testing short-term effects. The drugs may not work as hoped, and side effects are possible. Results may not apply to everyone with type 1 diabetes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Oregon Health & Science University
Portland, Oregon, 97239, United States
-
University of Michigan
Ann Arbor, Michigan, 48109, United States
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