Can a drug duo save insulin-making cells in type 1 diabetes?

NCT ID NCT05742243

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether combining two safe immune therapies—abatacept injections and nasal insulin—can help preserve the pancreas's ability to make insulin in people recently diagnosed with type 1 diabetes. The goal is to make blood sugar control easier and reduce the need for injected insulin. The trial involved 68 participants aged 6 to 21, who received treatment for 48 weeks and were followed for another 48 weeks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Perth Children's Hospital

    Nedlands, Western Australia, 6009, Australia

  • Queensland Children's Hospital

    South Brisbane, Queensland, 4101, Australia

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • The Royal Children's Hospital

    Parkville, Victoria, 3052, Australia

  • The Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • Women's and Children's Hospital

    North Adelaide, South Australia, 5006, Australia

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Other studies related to the condition(s) this trial covers.