Could the 'Love Hormone' help prevent dangerous low blood sugar in diabetes?

NCT ID NCT06881459

Completed Knowledge-focused Sponsor: University Hospital, Gentofte, Copenhagen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether oxytocin, a natural hormone, can improve the body's ability to release glucagon during low blood sugar (hypoglycemia) in people with type 1 diabetes. Sixteen adults with type 1 diabetes received both oxytocin and a placebo on separate days to compare their glucagon responses. The goal was to understand if oxytocin could help protect against dangerously low blood sugar levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Oxytocin
What this could lead to: If oxytocin boosts glucagon during hypoglycemia, it could point toward a new way to prevent dangerous low blood sugar in type 1 diabetes.
What could go wrong: This is a very small, early-stage study with only 16 participants. The effect may be small or not clinically meaningful, and oxytocin may cause side effects.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 1 DIABETES

Contacts and locations

Locations

Center for Clinical Metabolic Research, Gentofte Hospital

Hellerup, 2900, Denmark

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