Could a parathyroid gland help cure diabetes? small trial tests Co-Transplant
NCT ID NCT03977662
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small pilot study tested whether transplanting pancreatic islets together with parathyroid glands into the muscle could help people with type 1 diabetes stop using insulin. The 4 participants already had a functioning kidney or liver transplant and were on lifelong immunosuppression. The main goals were to check safety and see if the procedure leads to insulin independence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Co-transplantation of pancreatic islets and parathyroid glands from a deceased donor
What this could lead to
If it works, this could offer a way to achieve insulin independence in people with type 1 diabetes who already have a kidney or liver transplant.
What could go wrong
This is a very small pilot study with only 4 participants, so results may not apply to others. The approach requires lifelong immunosuppression, which carries risks of infection and other side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of California
San Francisco, California, 94143, United States